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Undetectable levels of HIV is untransmittable, say experts

ANI  |  Washington D.C. [USA] 

Officials from the National Institutes of have said that the results from years of clinical evidence that firmly established that the Undetectable = Untransmittable (U=U) concept is scientifically sound.

According to the experts, U=U means people living with who are able to achieve and maintain an undetectable viral load, i.e., the amount of in the blood, by taking and adhering to (ART) as prescribed cannot sexually transmit the virus to others.

The results, published in (JAMA), saw officials from and Infectious Diseases (NIAID) review the scientific evidence underlying the theory and discussing the implications of widespread acceptance of the message.

The new commentary saw NIAID Anthony S. Fauci, M.D., and colleagues summarize results from large clinical trials and cohort studies validating U=U. The landmark NIH-funded HPTN 052 clinical trial showed that no linked HIV transmissions occurred among HIV affected heterosexual couples when the partner living with HIV had a durably suppressed viral load.

Subsequently, the PARTNER and Opposites Attract studies confirmed these findings and extended them to male-male couples.

The NIAID officials note that the validation of the HIV strategy and acceptance of the U=U concept as scientifically sound have numerous behavioural, social and legal implications and can help control the HIV pandemic by preventing HIV transmission as it can reduce the stigma that many people with HIV face.

The success of U=U as an method depends on achieving and maintaining an undetectable viral load by taking ART daily as prescribed. However, there are multiple factors that can often make ART adherence difficult. To enhance the overall success of U=U, the authors emphasise the importance of implementing programmes that help patients remain in care and address the barriers to daily therapy.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Sat, January 12 2019. 12:20 IST
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