Top seed Juan Martin del Potro and No. 2 Andy Murray were both knocked out of the Rotterdam World Tennis in quarterfinals Friday.
The top two seeds were also upsetted by the same 6-3, 6-4 scorelines, reported Xinhua.
Latvian Ernests Gulbis beat the top seed, while unseeded Croatian Marin Cilic outplayed Murray to win his eighth match in a row this season, including a champion last week at home in Zagreb.
The Scot had claimed victory in nine of their 10 previous matches but was well off his game as he went out in 71 minutes, losing serve once in each set. Murray now has 10 days before his next start in Acapulco.
Third seed Tomas Berdych rallied to see off Poland's Jerzy Janowicz in nearly two-and-a-half hours in his 6-7 (9/11), 6-2, 6-4 comeback.
Dutchman Igor Sijsling beat German Philipp Kohlschreiber 6-2, 2-6, 6-1 to become the first home player to reach the last four here in more than a decade. He will next face Cilic.
Del Potro took treatment before the start of the second set on the left wrist which has been posing problems since last month in Australia.
He said he came to the match without the ability to hit a penetrating backhand as he plays with medical permission while trying to clear up his wrist problem.
He said he has felt delicate all week but still believes his dodgy wrist is on the mend.
"My doctor is confident and I will keep on playing tournaments as long as the wrist does not get worse," said the ATP No. 4.
"It's getting better very slowly but it can be tough to remain optimistic all the time.
"When you are not at 100 percent you are thinking about your problems instead of your tennis. That's what happening this week."
Murray is still recovering fitness after autumn back surgery and has not looked comfortable all week.
