From two-sets-to-love down, Murray had managed to wrench himself back into the contest, amid loud cheers from a 10,000-strong crowd at the Melbourne Arena, reports Efe news.
"I've honestly loved playing here over the years. It's an amazing place to play tennis. If this was my last match, (it's an) amazing way to end," Murray said in an on-court interview.
"I gave literally everything I had. It wasn't enough tonight," he said.
"Andy deserved all the people who came to watch him... it was an unbelievable match. Really good fight. He's a tough fighter, tough opponent, he gave everything until the last point," Bautista Agut said. "I want to congratulate him for all he did for tennis."
Bautista Agut will now play John Millman in the second round.
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