You are here: Home » News-IANS » Science-Tech
Business Standard

Scientists create 'most detailed' map of brain's memory bank

Topics
Health Medical Pharma

IANS  |  New York 

In a bid to better understand the brain region linked to Alzheimer's disease, scientists in the US have created what they believe to be the most detailed atlas yet of the brain's memory bank -- the hippocampus.

Created using fluorescent tracers and 3D animation, the map shows structures, nerve connections and functions of the hippocampus in vivid detail, according to the study published in the journal Nature Neuroscience.

"Like a new atlas, we've constructed the most detailed diagram of the hippocampus to date," said lead author of the study Michael Bienkowski from the Keck School of Medicine of the University of Southern California.

"With a better map, we can see each region and how it functions. A better map is a resource scientists can use to better understand the hippocampus and how its degeneration leads to diseases," Bienkowski said.

The human hippocampus sits at the base of the brain and it's shaped like a seahorse. It stores memories, helps regulate emotions and guides navigation by spatial processing.

It is the first part of the brain impaired by Alzheimer's and hippocampus degeneration can cause epilepsy and other diseases.

In this case, scientists worked on a mouse brain because it is organised similar to a human brain.

Scientists can use the new map of the hippocampus to deliver genetically-targeted drugs to specific neurons with fewer side effects, said senior author, Hong-Wei Dong, Professor of Neurology at USC.

Scientists have known the basic four-part architecture of the hippocampus for a long time.

But with the new map, scientists can show its sub-regions and how nerve cells interact across the structure.

"It totally changes our understanding by combining a wiring diagram with gene expression of the mouse hippocampus. We see it doing different things, and this gives us a new way to understand how the whole thing works together. This should have a very profound and broad impact," Bienkowski said.

--IANS

gb/bg

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

Dear Reader,


Business Standard has always strived hard to provide up-to-date information and commentary on developments that are of interest to you and have wider political and economic implications for the country and the world. Your encouragement and constant feedback on how to improve our offering have only made our resolve and commitment to these ideals stronger. Even during these difficult times arising out of Covid-19, we continue to remain committed to keeping you informed and updated with credible news, authoritative views and incisive commentary on topical issues of relevance.
We, however, have a request.

As we battle the economic impact of the pandemic, we need your support even more, so that we can continue to offer you more quality content. Our subscription model has seen an encouraging response from many of you, who have subscribed to our online content. More subscription to our online content can only help us achieve the goals of offering you even better and more relevant content. We believe in free, fair and credible journalism. Your support through more subscriptions can help us practise the journalism to which we are committed.

Support quality journalism and subscribe to Business Standard.

Digital Editor

First Published: Tue, October 09 2018. 18:46 IST
RECOMMENDED FOR YOU
RECOMMENDED FOR YOU