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Scientists create 'most detailed' map of brain's memory bank

IANS  |  New York 

In a bid to better understand the region linked to disease, scientists in the US have created what they believe to be the most detailed atlas yet of the brain's bank -- the

Created using fluorescent tracers and 3D animation, the map shows structures, nerve connections and functions of the in vivid detail, according to the study published in the journal Nature

"Like a new atlas, we've constructed the most detailed diagram of the to date," said of the study from the of the University of

"With a better map, we can see each region and how it functions. A better map is a resource scientists can use to better understand the hippocampus and how its degeneration leads to diseases," Bienkowski said.

The human hippocampus sits at the base of the and it's shaped like a seahorse. It stores memories, helps regulate emotions and guides navigation by

It is the first part of the impaired by and hippocampus degeneration can cause and other

In this case, scientists worked on a mouse brain because it is organised similar to a human brain.

Scientists can use the new map of the hippocampus to deliver genetically-targeted drugs to specific neurons with fewer side effects, said senior author, Hong-Wei Dong, at USC.

Scientists have known the basic four-part architecture of the hippocampus for a long time.

But with the new map, scientists can show its sub-regions and how nerve cells interact across the structure.

"It totally changes our understanding by combining a wiring diagram with of the mouse hippocampus. We see it doing different things, and this gives us a new way to understand how the whole thing works together. This should have a very profound and broad impact," Bienkowski said.



(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Tue, October 09 2018. 18:46 IST