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High-risk HPV may up heart disease risk: Study

Press Trust of India  |  Seoul 

with high-risk strains of the human (HPV), which have been linked to cancer, might increase the risk of cardiovascular disease, a study warns.

While has known risk factors -- such as cigarette smoking; high cholesterol, high blood pressure, physical inactivity, poor diet, and -- to prevent cardiovascular disease, it is important to uncover other potential contributors.

One potential contributor is the most common sexually transmitted worldwide -- the human or HPV, according to researchers from Hospital in South Korea.

Certain strains of are considered high risk because they can increase the risk of certain kinds of cancer, especially cervical, but also vaginal, vulvar, penile as well as mouth and throat.

A pap test can detect abnormal cells in the cervix, but often has no symptoms until cancerous cells develop.

In the study published in the journal Circulation Research, the team looked at the relationship between high-risk and diagnosed during the course of the study.

After adjusting for other factors -- such as body mass index (BMI), a weight-to-height ratio, smoking, alcohol use, exercise, education level and family history of -- women with high-risk HPV were 22 per cent more likely than uninfected women to develop cardiovascular disease.

The likelihood of cardiovascular disease rose even more when high-risk HPV occurred in conjunction with or

Comparing high-risk positive to high-risk HPV negative women, women with were nearly two-thirds more likely to develop cardiovascular disease, and those with and high-risk HPV were nearly twice as likely to develop cardiovascular disease.

Factors associated with a greater likelihood of high-risk HPV included current smoking and alcohol consumption. Interestingly, women who reported being physically active also were more likely to have high-risk HPV.

In contrast, higher education, defined as a college degree or more, was associated with a decreased likelihood of having high-risk HPV.

"A better understanding of high-risk HPV as a risk factor for cardiovascular disease and possible combined effects of high-risk HPV, obesity and in increasing cardiovascular disease risk may help improve preventive strategies and patient outcomes," said Seungho Ryu, a at Hospital.

"Further studies are required to identify specific high-risk HPV genotypes that may contribute to cardiovascular disease and to examine whether vaccine strategies to reduce for prevention may also help reduce cardiovascular disease," Ryu said.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Thu, February 07 2019. 18:30 IST