The 30-share index declined by 56.58 points or 0.17 per cent to 33,194.35. The gauge had gained 32.12 points in yesterday's highly volatile session.
All the sectoral indices led by metal, auto and oil & gas were trading in the negative terrain, falling by up to 0.92 per cent.
Asian Paint and Reliance Industries also dropped by 1.78 per cent, dragging the index into the negative zone.
Other major losers were Adani Ports, Axis Bank, TCS, Sun Pharma, Dr Reddy's, HDFC Ltd, Power Grid, M&M, Hero MotoCorp, Wipro and Infosys.
In other Asian markets, Hong Kong's Hang Seng index was down by 0.20 per cent, while Japan's Nikkei shed 1.38 per cent in early trade today. Shanghai Composite Index too was down 0.21 per cent.
The US Dow Jones ended lower by 0.43 per cent in yesterday's trade.
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)