Drug major Cipla today said it has received final approval from the US health regulator for tenofovir disoproxil fumarate tablets, used to treat HIV-1 infections in adults. Cipla in a BSE filing said it has received final approval from the United States Food and Drug Administration (USFDA) for tenofovir disoproxil fumarate tablets, 300 mg. These tablets are AB-rated generic equivalents of Gilead Sciences' Viread Tablets, 300 mg, and are indicated in combination with other antiretroviral agents for the treatment of HIV -1 infection in adults and paediatric patients 12 years of age and older. Citing IMS Health data, the company said Viread Tablets, 300mg, had US sales of approximately USD 725 million for the 12-month period ending November 2017. The company's stock was trading 0.55 per cent higher at Rs 621.55 per scrip on the BSE.
Pharmaceutical company Strides Shasun today said its wholly-owned subsidiary has received approval from the US health regulator for tenofovir disoproxil fumarate tablets, used to treat HIV-1 infections in adults. In a BSE filing, it said Strides Pharma Global Pte. has received approval from the United States Food and Drug Administration (USFDA) for tenofovir disoproxil fumarate tablets, 300 mg. The approved product is a generic version of Gilead's Viread tablets, for which patent expired on January 25. Strides Shasun, which already had tentative approval for the product from the USFDA, said it will launch the product immediately. Citing IMS sales data, the company said the US market for tenofovir disoproxil fumarate tablets is approximately USD 750 million. The company's stock was trading 1.90 per cent higher at Rs 806 on BSE.
According to a recent study, heavy periods might soon become a thing of the past.The University of Edinburgh researchers have developed a new drug that tricks the womb into healing faster, which stops your bleeding sooner, reports The Independent.The scientists explored how the shedding of the endometrium (the womb lining) is linked to dropping levels of oxygen during menstruation.The study discovered that lowered levels of oxygen - known as hypoxia - stimulates the production of a protein called HIF-1, which drives repair of the womb lining.Women with heavy periods had reduced levels of HIF-1 compared with women with normal blood loss, the findings showed.Tests on mice using a drug to boost levels of HIF-1 led to improved tissue repair and reduced blood loss. The results offer hope for therapies, the scientists noted.Researcher Dr Jackie Maybin said, "Our findings reveal for the first time that HIF-1 and reduced levels of oxygen in the womb are required during a period to optimise ...
Hormone changes caused by menopause make rheumatoid arthritis symptoms worse in women, according to a study.After studying 8189 women with rheumatoid arthritis, researchers found that pre-menopausal women experienced a slower physical decline than those that were post-menopausal.Physical function is an important aspect of study in patients with rheumatoid arthritis as it impacts their quality of life. Women experience rheumatoid arthritis at a rate three times greater than men, and also have more severe decline and increased disability, yet the sex-based differences in the condition remain poorly understood.Previous studies have shown that women with rheumatoid arthritis experience shifts in their disease surrounding reproductive and hormonal life events, such as childbirth.During pregnancy, women have decreased incidence of rheumatoid arthritis, yet they have an increased incidence of disease development and flare during the post-partum period.Similarly, women who experience early ...
Researchers in US have developed a superconducting switch that "learns" like its biological counterpart. The switch, called a synapse, could connect processors and store memories within future computers operating like the human brain.
Turns out, a single smoke can harm your body in ways incomprehensible to people.While we all are aware that smoking kills, the health risks just one single cigarette poses to your body has been brought to light by a new study.The researchers analysed 141 cigarette-smoking related studies and crunched the number of cigarettes people smoke and their subsequent health risks.It was discovered that the people who lit just one fag a day are 74 percent more likely to develop coronary heart disease than the people who do not smoke at all.Incidentally, people who smoke 20 cigarettes a day came out with double the chances of heart-related diseases than the non-smokers.It was also found that people who smoked just one cigarette a day were 30 percent more likely to have a stroke than non-smokers.The researchers reported that the chemicals in cigarette damage the function and structure of blood vessels, increasing the build-up of wavy plaque or the risk of arteriosclerosis.According to the ...
Researchers have found that when the health visitor uses video feedback in accordance with the Marte Meo -- a method of educational counselling -- as part of his/her work with the new mother, it strengthens the relationship between the infant child and the mother.
A man carrying a liquid oxygen cylinder was killed when he was yanked into the jaws of an MRI machine and inhaled the gas that leaked out of the container, his family said today. The police, however, said that Rajesh Maru (32) was killed last evening when he inhaled excessive oxygen that oozed out of the cylinder when he had entered the MRI room with a relative, who was there to undergo the scan. Metallic objects are not allowed in MRI rooms and the patient's family members said they were made to remove all such items, including mobile phone handsets, before entering inside. They claimed the ward boy said that the oxygen cylinder could be carried in the room as the machine was not switched on. The police have booked three staffers of Nair Hospital in Central Mumbai for culpable homicide not amounting to murder and arrested a doctor and a wardboy today, a police official said, adding that the role of the third accused, an ayah (sweeper), is being examined. "The victim, ..
A person injured in the recent Kasganj violence was blinded in one of his eyes despite efforts by doctors at the Jawaharlal Nehru Medical College Hospital here. 31-year-old Mohamed Akram was injured in the eye when he was caught in the violence while travelling from Aligarh to Lakhimpur Khiri on Friday night. Chief Medical Officer Dr Ahtesham told PTI, "Despite all efforts, we could not save his eye which was injured by a sharp object. He is, however, out of danger and recovering from other injuries." Besides Akram, another man, Naushad, had received a gunshot wound on his leg during the Kasganj violence was undergoing treatment at the Jawaharlal Nehru Medical College here. He too is out of danger, officials said.
Scientists have discovered a new source of neurotoxin, known for its paradoxical ability to remove wrinkles yet cause an illness associated with food poisoning from a strain of animal gut bacteria, a finding that can potentially expand its therapeutic applications.
To prevent the risk of dementia in old age, here are eight lifestyle changing tips that can help in the long run.Although, research has not yet discovered a cure for dementia, changes in diet, exercise and daily routine can reduce the risk factors, reports express.co.uk.Here's a step by step guide to prevent dementia - which includes getting a good night's rest.Sleep wellDisrupted sleep patterns and insomnia have recently been suggested as risk factors for dementia. You may want to do regular exercise and eat healthy to improve sleep patterns. If you are having problems sleeping speak to your GP.Eat omega-3 fatsResearch has proven that the DHA in omega-3 fats reduces the risk of dementia.Try including fish for dinner at least twice a week. Nuts and seeds are also rich in omega-3 goodness and taste delicious when added to your breakfast cereal.Exercise regularlyRegular exercise has been known to cure most ailments, and when you are older it is even more beneficial.Exercising at least ..
The future of medicine in India is likely to combine the benefits of traditional medicine with alternative practices like energy healing, experts at a quantum energy forum said here.
Eating turmeric daily may boost your memory and uplift your mood, a study suggests. Found in turmeric, curcumin has previously been shown to have anti-inflammatory and antioxidant properties. It also has been suggested as a possible reason that senior citizens in India, where curcumin is a dietary staple, have a lower prevalence of Alzheimer's disease and better cognitive performance. "Exactly how curcumin exerts its effects is not certain, but it may be due to its ability to reduce brain inflammation, which has been linked to both Alzheimer's disease and major depression," said Gary Small, from the University of California, Los Angeles in the US. The study, published in the American Journal of Geriatric Psychiatry, involved 40 adults between the ages of 50 and 90 years who had mild memory complaints. They were randomly assigned to receive either a placebo or 90 milligrammes of curcumin twice daily for 18 months. All 40 subjects received standardised cognitive assessments
Older adults who are frail are twice as likely to experience delirium following elective surgery than those of an older age, a study has found. Researchers found that a history of delirium, frailty and cognitive impairment are the risk factors most strongly associated with developing postoperative delirium. Previous research has found that frailty and cognitive impairment before surgery are associated with developing complications after surgery, but age is not. Other risk factors that are associated with developing postoperative delirium include smoking and the use of psychotropic medications, the researchers said. "Chronological age from your birth date is not always an accurate assessment of how you've aged over your lifetime," said Jennifer Watt, from the St. Michael's Hospital in Canada. "This study highlights how common delirium is among older adults undergoing elective surgery, and the importance of geriatric syndromes, including frailty, in identifying older adults
The proposal by the All India Institute of Medical Sciences (AIIMS) to do away with user charges on diagnostic procedures like blood tests and X-rays, which cost less than Rs 500 will take more time to become a reality. While the institute has conducted a pilot study to justify its proposal and submitted the same to the health ministry, the administration has now sought details of the user fees charged for each tests from each department. According to a source at AIIMS, the proposal has been submitted to Health minister J P Nadda but there has been no development on it. On directives from the finance ministry, the health ministry had repeatedly asked the hospital to review and revise user charges unchanged in the past 20 years.The cost of many routine tests at AIIMS ranges between Rs 10 and Rs 25. A committee headed by Dr Anoop Saraya, head of department of Gastroenterology at the AIIMS was constituted to review the user fee charges at the hospital and had submitted its .
More than 10,000 children participated in the 20th Terry Fox run organised in Mumbai's Marine Drive area on Sunday morning.Canadian Consul General Jordan Reeves for the awareness of cancer flagged off the event.The main purpose of this run is to spread awareness about cancer.Talking to ANI, Reeves said, "People are very excited to participate in this run. This run is one of the largest run as more than 10, 000 children are participating in it to make people aware about cancer. We are here to raise as much money as possible for cancer research.""Our intention is to tell the whole Mumbai that we can defeat cancer. We donate the collected amount to Tata Memorial and other hospitals. These hospitals use money for cancer reserach, so that we can defeat cancer," Gul Kriplani, a Terry Fox member said.The runs first began when Terry Fox, a 22-year-old Canadian whose leg had to be amputated due to osteosarcoma (bone cancer), embarked on the Marathon of Hope in 1980. Later, he eventually died ..
Ever wondered, how people remember their childhood birthday parties or wedding days?According to researchers from the University of Colorado at Boulder, a protein called AKT, which is ubiquitous in brain tissue and instrumental, enables the brain to adapt to new experiences and lay down new memories.They showed that AKT comes in three distinct varieties residing in different kinds of brain cells and affecting brain health in very distinct ways.The discovery could lead to new, more targetted treatments for everything from the brain cancer to Alzheimer's disease and schizophrenia.Study author Charles Hoeffer said, "AKT is a central protein that has been implicated in a bevy of neurological diseases yet we know amazingly little about it".AKT has more recently been identified as a key player in promoting "synaptic plasticity," the brain's ability to strengthen cellular connections in response to experience."Let's say you see a great white shark and you are scared and your brain wants to ..
Scientists have identified seven bacterial species whose presence in high concentrations may significantly increase the risk of HIV infection in women. The findings add strength and precision to a growing body of evidence that the makeup of bacterial communities in the vagina - the vaginal microbiome - may increase or decrease HIV risk for women, depending on which bacteria are there. The researchers from the Fred Hutchinson Cancer Research Center in the US said the results could lead to a better understanding of how biological conditions may promote infection by the virus that causes AIDS, and perhaps offer targets for future prevention research. Of seven bacterial species linked to higher risk, the most conspicuous of them is Parvimonas Type 1, an otherwise common bug not considered particularly worrisome, according to the study published in the journal The Lancet Infectious Diseases. However, the researchers found that women carrying high concentrations of that bug ...