US space shuttle Endeavour leaves International Space Station

US space shuttle Endeavour and its crew of six departed from the International Space Station and headed back to Earth wrapping up NASA's next-to-last shuttle flight.

The undocking took place at 11:55 pm (0355 GMT today), at a time when the space station and shuttle was be 215 miles (350 kilometres) over La Paz, Bolivia, NASA said.

The six-member crew of the Endeavour- five US astronauts and Italian Roberto Vittori- bid farewell to three colleagues on board the space station (ISS) and closed the hatches between the shuttle and station at 7:23 am (1123 GMT) yesterday.

The parting goodbyes between the ISS crew and the six members of the Endeavour crew,led by shuttle commander Mark Kelly,took place around 7 a m EDT yesterday, terminating around 11 total days of connection between the two spacecraft.

Kelly was the final crew member to walk- er, float- off the ISS.

"We're looking forward to getting home," Kelly said, "and we're going to leave these guys to some peace and quiet and not disturb their space station any more".

In total, the Endeavour crew has been on four spacewalks and has performed a series of equipment installations as part of Endeavour's final mission.

The astronauts delivered a $2 billion cosmic ray detector to the International Space Station- the Alpha Magnetic Spectrometer-2- whose 15,251 pounds of magnets and detectors are designed to assist researchers in searching for 'unusual' types of matter.

The six crew members now face two days of travel before NASA's second-to-last manned shuttle mission arrives back on the planet.

Endeavour's 16-day mission began with the shuttle's launch from Cape Canaveral, Florida on May 16 and will conclude when the shuttle lands back on Earth early on June 1.