Nathan Tumuhamye, director of an organisation which helps communities recover from natural disasters and conflict, told AFP that "four to five villages", and possibly a primary school had been affected.
Uganda Red Cross spokeswoman Irene Nakasiita on Thursday shared photos of the scene of what she described as a "massive landslide" on WhatsApp, including images of dismembered corpses caked in mud laid out by the river.
Some of the bodies have been partly covered with banana leaves by members of the public.
"I have received the sad news of landslides wreaking havoc in Bududa District, killing a yet-to-(be)specified number of residents. The government has dispatched rescue teams to the affected areas," President Yoweri Museveni wrote on Twitter.
At least 100 people were reported killed in a landslide in Bududa in March 2010 and in 2012 landslides destroyed three villages.
Government efforts to move vulnerable people to neighbouring districts have faced resistance from residents.
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)