"As we continue our Cricket World Cup preparations, the upcoming series against the top ranked ODI side is a great opportunity for us to gauge where we are as a team," said West Indies chairman of selectors Courtney Browne.
"This allows us to identify any areas that need addressing relating to selection and also helps the coaching staff to fine tune their game strategy."
Gayle holds the West Indian record for most ODI hundreds with 23, and is their second-leading runscorer in the 50-over format with 9,727 runs -- trailing only Brian Lara (10,405).
"He is clearly a young player with undoubted talent and we believe he can add value to our middle order."
Browne said fast bowler Shannon Gabriel would be considered for later in the series, although experienced batsman Marlon Samuels is unavailable due to a knee injury.
Squad: Jason Holder (captain), Fabian Allen, Devendra Bishoo, Darren Bravo, Chris Gayle, Shimron Hetmyer, Shai Hope, Evin Lewis, Ashley Nurse, Keemo Paul, Nicholas Pooran, Rovman Powell, Kemar Roach, Oshane Thomas
Fixtures: 1st ODI - February 20, Bridgetown 2nd ODI - February 22, Bridgetown 3rd ODI - February 25, St George's 4th ODI - February 27, St George's 5th ODI - March 2, Gros Islet.
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