The 43-year-old actor, who plays the villainous Nimue the Blood Queen in the David Harbour-starrer film, took to Instagram to address the critics.
"It's always stressful on opening weekend and 'Hellboy' is no different. You work super hard to make something fun and entertaining and have to absorb the negative reviews by movie critics, but hey! That's showbiz baby," she wrote in a post.
"All I'm gonna say before going to bed is this: All my raddest films have been slammed by critics. It's f***ing hilarious," she added.
She said people will "have a blast watching" the new "Hellboy".
As she concluded her post, the actor took an aim at a critic, who had labelled the film as "a loud, gory mess only a teenager would love".
"HELL yea 'Hellboy'! Let's have some fun! And with that, I wish you all a good night!," Jovovich said.
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