The two sides split after a civil war in 1949, but Beijing still sees the self-ruling island as part of its territory to be brought back into the fold.
Beijing has also made progress with the Vatican, Taiwan's most powerful official ally and its only one in Europe, by signing a landmark agreement with the Holy See on the appointment of bishops last year.
"We believe that this visit will increase the understanding of Taiwan among the people in these countries ... and for Taiwanese people to get familiar with our good friends."
Tsai, Taiwan's first female leader, will also meet with Marshall Islands President Hilda Heine, the first female head of state in the Pacific islands and join a women leaders' conference hosted by the country, Hsu added.
He declined to give details about where Tsai will transit, saying it is "pending negotiation." Taiwan is typically low-key in announcing its leader's specific itineraries, fearing China's use of its power to disrupt.
Tsai's last state visit was to Paraguay in August with US transits that prompted an official protest from Beijing after she gave a speech in Los Angeles -- the first time in 15 years that a Taiwanese leader spoke publicly on US soil.
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