The accident took place at Bharregaon Phata on NH-6 around 11.30 pm on Wednesday, police said.
"The tractor, which was carrying a small harvester machine as well as some people, was going to Sirpurbandh in the district. When it reached Bharregaon Phata, a truck transporting iron pipes to Odisha from Mumbai rammed into the tractor from behind," a police official said.
"The tractor overturned due to the impact and its driver and another man travelling in it died on the spot. Five other occupants suffered critical injuries in the incident and they were rushed to the rural hospital in Deori," he added.
One of the injured was later shifted to Nagpur for further treatment, police said.
The driver of the truck, Babu Janrao Dongre (26), was later arrested, police said, adding that further investigation into the case was on.
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)