Page 318 - Health Medical Pharma
Youth hormone necessary for conceiving after 40
DHEA (dehydroepiandrosterone), also known as the youth hormone is an adrenal steroid hormone in the body synthesized by the adrenal glands, which are then converted into androgens, estrogen, and other hormones.These hormones are responsible to regulate fat and mineral metabolism, sexual and reproductive function, and energy levels. The level of DHEA increases until our body is in the late 20s, after which it starts declining with age."DHEA supplements help by increasing the androgen levels within the ovarian environments to a normal range, which improves egg quality. The high-quality healthy eggs develop into high-quality embryos, which have a better chance of implantation and lower risks of miscarriage," said Dr. Sowjanya Aggarwal, Gynaecologist, Max Hospital, Vaishali."DHEA supplements diminish ovarian reserve (DOR) through the practice of In Vitro Fertilisation (IVF). The pregnancy outcomes have been improved for those who suffer from premature ovarian aging (POA) as well as women .
Genes determine how heart rate responds to exercise
When people exercise, their heart rate and blood pressure increase. However, the magnitude of this is different for different people.Genes can determine how the heart rate and blood pressure respond to exercise and may act as an early warning of future problems for the heart or blood vessels, according to new research.Previous research has shown that abnormally large increases in blood pressure during exercise makes it more likely that people will suffer from future high blood pressure. Therefore understanding why people react differently to exercise is important as this can help to identify risk factors and enable early monitoring or treatment of individuals at risk.Until now it has not been known why the response to exercise varies between different people. This new research has found that genetic differences in receptors found in skeletal muscles can contribute to this different response.Receptors are groups of specialised cells that detect changes in the environment and cause some
IL&FS Transportation Networks gets revision in credit ratings
From CARE and ICRA
Active kids may have a healthier heart
According to the latest research, adolescents with better aerobic fitness have more compliant arteries than their lower fit peers do. The study also suggests that a higher anaerobic threshold is linked to better arterial healthArterial stiffness is one of the first signs of cardiovascular disease, and adults with increased arterial stiffness are at higher risk of developing the clinical cardiovascular disease. However, arterial stiffening may have its origin already in childhood and adolescence.Dr Eero Haapala, one of the lead researchers said, "In our study, we showed for the first time that the anaerobic threshold is also related to arterial stiffness."Anaerobic threshold describes the exercise intensity that can be sustained for long periods of time without excess accumulation of lactic acid. The study showed that adolescents with a higher anaerobic threshold also had lower arterial stiffness than other adolescents did."The strength of determining anaerobic threshold is that it ...
Back pain and unhealthy behavior go hand in hand
A new study indicates that adolescents who experience back pain more frequently are also more likely to smoke cigarettes, drink alcohol, and report problems like anxiety and depression.During adolescence, the prevalence of musculoskeletal pain (pain arising from the bones, joints or muscles) in general, and back pain, in particular, rises steeply. Although often dismissed as trivial and fleeting, adolescent back pain is responsible for substantial health care use, school absence, and interference with day-to-day activities in some children.The study aimed at determining whether adolescents who experience back pain more often were also more likely to report other health risk indicators, such as alcohol use, smoking, school absenteeism, and depression or anxiety.The researchers used data collected from approximately 6500 teenagers. The proportion of participants reporting smoking, drinking, and missing school rose incrementally with increasing frequency of pain. For example, ...
J&J case: Govt asks 'victims' to approach central or state panel
The government Tuesday issued a public notice stating that patients suffering from disability due to faulty articular surface replacement (ASR) hip implants can approach either the central expert committee or the state-level panel. In case the affected patients intend to approach the central expert committee, they may write to the legal cell of the Central Drugs Standard Control Organisation, FDA Bhavan on Kotla Road, New Delhi. They may send an email on legalcell@cdsco.nic.in. If the affected patients approach the state-level committee, they may write to the concerned state drug controller who will be the member secretary of the state-level committee. The Centre, earlier this month, constituted the central expert committee under the chairmanship of R K Arya, director of Sports Injury Centre at Safdarjung Hospital, to determine the quantum of compensation to be given to patients who have faulty hip implants, manufactured by DePuy International, a subsidiary of Johnson & ...
Woman donates kidney to save life of junior colleague
The city has witnessed an example of camaraderie when a 40-year-old woman donated her kidney to a junior colleague to save her life, doctors at the reputed hospital here said Tuesday. The patient, a resident of Jharkhand, was suffering from a chronic kidney disease and was advised by the doctors to undergo kidney transplantation urgently as her health situation deteriorated. As the criteria did not match with any one of her family, her colleague in the Bengaluru-based IT firm came forward, a senior doctor at the at Fortis Hospital & Kidney Institute (FHKI), where the transplantation took place, said. "She was undergoing dialysis regularly while waiting for a suitable donor. As none from her immediate family could donate due to medical issues, this senior colleague from her office decided to donate one of her kidneys to save her," the doctor said. The transplantation surgery took place on September 3. "It is a great example when one comes forward to donate her kidney .
Cipla gets South African regulator's approval for new HIV drug
Drug maker Cipla said Tuesday its South African subsidiary has received approval from the country's health regulator for the latest first-line triple-combination antiretroviral (ARV) treatment for HIV. The approval granted by South African Health Products Regulatory Authority (SAHPRA) is for new combination medicine commonly referred to as TLD -- a combination of tenofovir (TDF), lamivudine (3TC) and dolutegravir (DTG), the company said in a statement. "In future, TLD will be manufactured at Cipla's facilities in Durban and Uganda," it said, adding that it would reinforce the company's commitment to produce medicines in Africa for Africa and ensure more affordable treatment for patients. Commenting on the development, Cipla South Africa CEO Paul Miller said DTG is considered a best-in-class medicine providing many clinical benefits for people living with HIV. "With DTG replacing efavirenz (EFV) in the first-line fixed dose combination treatment thereby reducing the likelihood of ...
USFDA conducting inspection of Mohali plant: Sun Pharma
Drug major Sun Pharmaceutical Industries Tuesday said the US health regulator is conducting an inspection of its Mohali facility in Punjab. The inspection by the United States Food and Drug Administration (USFDA) started on September 10, 2018 and is ongoing, Sun Pharma said in a filing to BSE. The company, however, did not provide any further details of the inspection. In 2017, the US regulator had proposed to lift import alert on Mohali-based plant. The USFDA, in September 2013, had issued an import alert on drugs produced at the then Ranbaxy's Mohali plant for violation of current good manufacturing practices. Last week, the USFDA had issued Form 483 with six observations after an inspection of the company's Halol facility in Gujarat. The US regulator had conducted a pre-approval inspection (PAI) of the Halol plant in August, Sun Pharma had said in a regulatory filing. Shares of Sun Pharmaceutical Industries today closed at Rs 631.05 per scrip on BSE, down 1.32 per cent from its ...
Narayana Hrudayalaya inks pact with Bangladesh-based Imperial Hospital
Healthcare provider Narayana Hrudayalaya Tuesday said its subsidiary NH Health has entered into an agreement with Bangladesh-based Imperial Hospital. NH Health Bangladesh Pvt Ltd, a foreign step-down subsidiary of the company has entered into an operation and management agreement with Imperial Hospital Ltd, Narayana Hrudayalaya said in a filing to BSE. Under the pact, NH Health Bangladesh will operate and manage the cardiac sciences department of a unit of the Imperial Hospital Ltd being set-up in Chittagong on a revenue sharing basis, it added. Shares of Narayana Hrudayalaya today closed at Rs 249.15 per scrip on BSE, down 1.50 per cent from its previous close.
NH Health Bangladesh partners with Imperial Hospital in Chittagong, Bangladesh
To operate and manage Imperial Hospital's Heart Centre
Nawaz Sharif's wife passes away
Former three-time Pakistan prime minister Nawaz Sharif's wife, Kulsoom Nawaz, breathed her last at a London hospital on Tuesday. She was 68 years old.Geo News reported that the health of Kulsoom, who was admitted at London's Harley Street Clinic for cancer treatment in June, deteriorated last night. She was placed on life support earlier in the day.Sources added that she had also developed a lung-related problem.In August 2017, it was confirmed that Kulsoom was suffering from lymphoma (throat) cancer and was shifted to London for further treatment. On June 15, she was placed on a ventilator following a cardiac arrest.She served as Pakistan's first lady for three non-consecutive terms from 1990-1993, 1997-1999 and 2013-2017, The Dawn reported.Kulsoom is survived by her husband and four children - Maryam, Hassan, Hussain and Asma. Her husband and daughter are presently serving jail terms after being convicted for corruption.
HC turns down rape survivor's plea to terminate pregnancy
The Bombay High Court has refused permission to a 17-year-old rape survivor to medically terminate her 20-week pregnancy. In an order passed on Monday, a bench of Justices A S Oka and M S Sonak turned down the girl's plea after noting that a panel of medical experts had ruled that considering the late stage of her pregnancy, an abortion would pose a major risk to the life of the petitioner. The petitioner had approached the court last week seeking that she be permitted to medically terminate the pregnancy despite the medical panel's recommendation. She had argued that forcing her to continue with the pregnancy would be adverse to her mental health and well-being, and that the same would cause her much trauma. The bench, however, noted that in view of the opinion by a medical board of Pune's Sassoon Hospital, which said that a medical termination could pose a risk to her life, it was "impossible for this court to permit MTP". It also said that there was no material on record to show ...
'New drug may help treat tuberculosis'
Scientists say they have developed the first non-antibiotic drug to successfully treat tuberculosis (TB) in animals. Researchers at The University of Manchester in the UK hope the compound developed after 10 years of painstaking research will be trialled on humans within three to four years. The drug works by targeting Mycobacterium tuberculosis' defences rather than the bacteria itself. The drug can also take out its increasingly common antibiotic resistant strains, according to the research published in the Journal of Medicinal Chemistry. Although a vaccine for TB was developed 100 years ago, one in three people across the world are thought to be infected with the infectious disease, researchers said. About 1.7 million die from the bug each year worldwide and 7.3 million people were diagnosed and treated in 2018, up from the 6.3 million in 2016, they said. The researchers said TB is most common in Africa, India and China, but on the rise in the UK with London often described as the .
Back pain linked to risky behaviours in teenagers: Study
Does your adolescent son or daughter suffer from back pain often? Beware, he or she may be more likely to smoke cigarettes, drink alcohol, and report problems like anxiety and depression.
How binge drinking affects male, female brains?
While binge drinking affects health of both males and females, the effect of gene expression in an area of the brain linked to addiction was found to be different, finds a new study.
Novel drug may offer treatment for TB
In a first, British scientists have developed a non-antibiotic drug that can one day successfully treat tuberculosis (TB) in humans.
'Indian-American scientist awarded $6.5 million for cancer biomarkers'
An Indian-American scientist has been awarded USD 6.5 million to identify cancer biomarkers which may improve diagnosis and help develop new targeted therapies for the deadly disease. The grant awarded by the US National Cancer Institute to Arul Chinnaiyan, a professor at University of Michigan, will provide long-term support to increase understanding of these markers to leverage targeted treatments for cancer. Chinnaiyan has received an 'Outstanding Investigator Award' from the National Cancer Institute, which provides USD 6.5 million in funding over seven years, the University of Michigan said in a statement. "The field of precision oncology continues to evolve with the overarching goal of providing cancer patients with enhanced diagnostic and prognostic capabilities and better treatments," said Chinnaiyan, a professor of Pathology at the University of Michigan Medical School. "This grant will help us identify new biomarkers and understand their biological roles in cancer ...
Neutralising antibodies offers hope for HIV vaccine
Researchers are in the process of discovering the factors responsible for the production of antibodies that do not just fight one virus strain, but neutralises almost all known virus strains.
Indian-American researcher awarded $6.5Mn to identify cancer biomarkers
The US National Cancer Institute has give the "Outstanding Investigator Award" to Professor Arul Chinnaiyan, from the University of Michigan, and $6.5 million in funding over seven years, to identify cancer biomarkers to improve diagnosis and develop new targeted therapies.