You are here: Home » Current Affairs » Coronavirus » News
Business Standard

Omicron's latest subvariant BA.2.12.1 proves virus not declining: Report

Omicron's latest subvariant BA.2.12.1, responsible for about one-fourth of Covid-19 cases in the US, shows that the virus is not showing any signs of decline even over two years

Coronavirus | Omicron | Covid-19 XE Variant

IANS  |  New York 

Photo by Viktor Forgacs on Unsplash
Photo by Viktor Forgacs on Unsplash

Omicron's latest subvariant BA.2.12.1, responsible for about one-fourth of Covid-19 cases in the US, shows that the virus is not showing any signs of decline even over two years after it was first detected in humans.

BA.2.12.1 has also been detected in Australia and New Zealand.

Preliminary research suggests it is about 25 per cent more transmissible than the BA.2 subvariant that is currently dominant nationally, according to the Centers for Disease Control and Prevention.

According to virologists, although the SARS-CoV-2 virus has repeatedly changed its structure and chemistry, it still has abundant evolutionary space to explore, Washington Post reported.

While existing vaccination can still reduce the risk of severe Covid disease, the variants can evade many of the neutralising antibodies that are the immune system's front line of defence.

"It's evolving at a fairly rapid rate. I do think we need to aggressively consider whether we should update vaccines, and do it soon," Jesse Bloom, a computational biologist at the Fred Hutchinson Cancer Research Center in Seattle was quoted as saying.

"The evolution is much more rapid and expansive than we initially estimated," added Michael Osterholm, infectious-disease expert at the University of Minnesota.

"Every day I wake up, I fear there will be a new subvariant that we will have to consider. . . We're seeing sub-variants of sub-variants," he added.

Other mutations include BA.4 and BA.5, recently identified by scientists in South Africa. It has led to a fresh wave of Covid in the country.

Besides South Africa, the sub variants have also been detected in more than 20 countries including Australia, Austria, Belgium, China, Israel, Denmark, France, Germany, Pakistan, UK, US and Switzerland.

Apart from mutation, the virus has another trick up its sleeve: recombination. It happens when two distinct strains infect a single host simultaneously and their genes become entangled, the Post reported.

The recombination process is the origin of what's known as XE. That recombinant probably emerged from a person co-infected with the original variant and the BA.2 subvariant.

It was always possible in theory, but the identification of actual recombinants provides "proof of concept," Jeremy Luban, a virologist at the University of Massachusetts Medical School was quoted as saying.

The worst-case scenario would be the emergence of a variant or recombinant that renders current vaccines largely ineffective at blocking severe disease. But so far, that hasn't happened. And no "recombinant" has spread like or other recent variants and sub-variants, the report said.



(Only the headline and picture of this report may have been reworked by the Business Standard staff; the rest of the content is auto-generated from a syndicated feed.)

Dear Reader,

Business Standard has always strived hard to provide up-to-date information and commentary on developments that are of interest to you and have wider political and economic implications for the country and the world. Your encouragement and constant feedback on how to improve our offering have only made our resolve and commitment to these ideals stronger. Even during these difficult times arising out of Covid-19, we continue to remain committed to keeping you informed and updated with credible news, authoritative views and incisive commentary on topical issues of relevance.
We, however, have a request.

As we battle the economic impact of the pandemic, we need your support even more, so that we can continue to offer you more quality content. Our subscription model has seen an encouraging response from many of you, who have subscribed to our online content. More subscription to our online content can only help us achieve the goals of offering you even better and more relevant content. We believe in free, fair and credible journalism. Your support through more subscriptions can help us practise the journalism to which we are committed.

Support quality journalism and subscribe to Business Standard.

Digital Editor

First Published: Mon, May 02 2022. 19:34 IST