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Childhood stress linked to brain disorders later: Study

IANS  |  New York 

Excessive in early childhood can increase the likelihood of brain and affects an individual's response to as an adult, says a new study.

The study, on a mouse model, found that childhood increases the chance of developing anxiety, depression, or later in life by two to four times.

In addition, maternal stress during pregnancy may increase the child's risk of developing (ASD) affecting communication and behaviour, psychiatric illnesses, and can also lead to changes in the nutrients a mother passes on to her babies in the womb.

"Understanding how stress impacts developing may lead to new, patient-specific approaches to treatment and better outcomes," said Heather Brenhouse, postdoctoral student from the in the US.

Further, early life stress was found to change chromatin structure in a brain reward region in mice, making them more vulnerable to stress as adults.

Early life stress also accelerates the development of the fear response in young mice. However, the effect can be prevented by blocking stress hormone production, according to the study.

Scientists are discovering more about the mechanisms through which childhood or foetal stress disrupts brain development and leads to these disorders, which may help reveal new therapeutic strategies, the team noted.

The results were presented at 2018, the annual meeting of The Society for (SfN) in

The research also suggests novel approaches to combat the effects of stress, such as inhibiting stress hormone production or "resetting" populations of immune cells in the brain.

For ASD caused by during pregnancy, renewing foetal brain immune cells can alleviate symptoms of the



(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Tue, November 06 2018. 14:18 IST