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Ketamine can cut depression, suicidality rapidly: Study

IANS  |  New York 

Recreational drug is likely to have fast-acting benefits in treating symptoms of depression as well as reducing suicidal thoughts, say researchers, including one of an Indian-origin.

The findings of the trial, published in the American Journal of Psychiatry, showed use of Ketamine, also licensed as an anaesthetic, through a nasal spray, led to significant improvements in depressive symptoms and reduction in suicidal thoughts in the first 24 hours.

could be an important treatment to bridge the gap as it can help in the rapid treatment compared to the delayed effects of most common antidepressants, which take four to six weeks to become fully effective, said Jaskaran B. Singh, from the in San Diego, US.

The results support nasal spray as a possible effective rapid in patients assessed to be at imminent risk for suicide, the researchers noted.

For the study, a small group of participants randomly assigned to one of two groups - either receiving or placebo twice a week for four weeks, and found a significant improvement in depression scores and decreased in the esketamine group compared to the placebo group at four hours and at 24 hours.

However, at 25 days, the effects had levelled out.

While there esketamine dependence or misuse was not observed in the trial, the researchers suggested for effective controls on the distribution and use of

They argued that steps to control the use of would not be aimed at preventing its use for beneficial purposes but would allow for treatment to "continue to be available to those with need, while the population that is at-risk for abuse is protected from an epidemic of misuse."

--IANS

rt/vd

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Mon, April 16 2018. 17:32 IST
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