In the film, directed by Tony Cervone, Wahlberg will play the Blue Falcon, a superhero from the Hanna-Barbera canon who teams with Scooby-Doo and the Mystery Gang to fight against one of his arch-enemies, Mr Hyde.
Ken Jeong is voicing, Blue Falcon's right hand Dynomutt, reported Deadline.
Isaacs will play Dick Dastardly, who is reported to be the main villain in "Scoob".
The film's voice cast also features Zac Efron (Fred), Amanda Seyfried (Daphne), Gina Rodriguez (Velma), Will Forte (Shaggy), Tracy Morgan (Captain Caveman), Frank Welker (Scooby-Doo) and Kiersey Clemons (Dee Dee Skyes).
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)