This is the second such incident this week on the Haji Malang Road.
On Sunday, a 43-year-old woman riding pillion on a motorcycle fell off due to a crater and was crushed under wheels of a bus. The video of the incident had gone viral.
In the latest incident, which occurred yesterday, the man was walking towards a cowshed in Balgaon area when he lost his footing and fell into a water-filled crater at Dwarli Naka, the official said, adding that a truck coming from behind ran him over.
The deceased is identified only as Anna.
Khan is a resident of Rabodi area in Thane.
Many streets in Mumbai remained under water earlier this week due to incessant rains.
As rains took a break yesterday and water receded, many potholes have resurfaced on the city roads.
The Mumbai Congress has alleged that four persons have died in potholes-related accidents in various areas of the city.
The city unit today launched a campaign to highlight the "inaction" of the BMC into the matter.