Scientists have used engineered mice to compare SARS-COV-2 Omicron subvariants and found that the BA.5 strain was more virulent likely due to its ability to rapidly replicate early during infection. The research, published in the journal Science Advances, addresses a challenge to studying and understanding rapidly evolving variants of concern due to a lack of animal models for running tests that could help explain why variants and subvariants each behave differently in people. The genetically modified mice, called K18-hACE2, used in the research express a human receptor that allowed SARS-COV-2 to enter otherwise inaccessible mouse cells. "One of the things we found is that the strain that causes more pathology, BA.5, replicates much faster early on during infection," said Avery August, a professor in the College of Veterinary Medicine (CVM) at Cornell University in the US. "By doing that, the virus generates a really strong immune response, which then leads to increased pathology a
Scrub typhus is caused by a bacteria, Orientia Tsutsugamushi, and is an infectious illness. People with severe illness may develop organ failure and bleeding, according to doctors
Encephalitis (inflammation of the brain) is a potentially fatal complication of Nipah virus. Patients with breathing complications are more likely to transmit the virus than those without
Mumbai doctors say that in the last one or two weeks there has been a 20-25 per cent surge in such cases, and most of the patients are children
The Delhi government has come up with a "mega action plan" to combat the spread of vector-borne diseases, under which steps will be taken to determine the serotype of the prevailing dengue virus in the city. Delhi Health Minister Saurabh Bharadwaj on Sunday chaired a high-level meeting on preparedness for keeping vector-borne diseases under check in the national capital. One of the significant decisions taken in the meeting was to "determine the serotype of the prevailing dengue virus" in identified laboratories, the Delhi health department said in a statement. "This step will provide crucial information for developing targeted interventions and enhancing the effectiveness of disease management efforts," it said. According to data shared by civic authorities, 136 cases of dengue and 43 of malaria have been recorded in Delhi this year till July 8. The existing helpline -- 1031 -- used during the COVID-19 pandemic will now be utilised to facilitate dengue treatment. This expansion o
Guillain-Barre Syndrome (GBS) is a rare disorder that affects the immune system causing it to attack the nerves of the body
The costs required to reduce the risk of sickle cell disease is beyond the reach of most individuals in India and sub-Saharan Africa, where the disease is most prevalent, says a new Commission published in The Lancet Haematology journal. The Commission publishes shortly after a recent study in the same journal found that the highest burden of sickle cell disease (SCD) disability was concentrated in western and central sub-Saharan Africa and India. The authors of the Commission also noted that there is a shortage of healthcare and scientific professionals with expertise in SCD, as well as a lack of trials aimed at developing novel treatments in these countries. SCD is a group of inherited red blood cell disorders that affect hemoglobin, the protein that carries oxygen through the body. The condition affects more than 20 million people worldwide. The recent study suggested there were 376,000 (3.76 lakh) global SCD-related deaths in 2021, compared to 34,400 cause-specific ...
As many as 60 sheep and goats were killed and around 200 affected following the outbreak of a highly contagious animal disease in the highland pastures of the tribal Lahaul and Spiti district of Himachal Pradesh, officials said on Monday. The Peste des Petits Ruminants (PPR) disease, also known as 'sheep and goat plague', has affected the cattle of three identified flocks in the Hadsar area near Chamba border. The common symptoms of the disease are diarrhoea and pneumonia affecting the lungs, Dr Anurag, a veterinarian treating the animals along with his four-member team, told PTI. The animals also experience nasal discharge leading to breathing problems, especially for affected animals in high altitude areas, Anurag said. Besides treating the sick sheep and goats and providing their owners with medical kits, the veterinary team is also raising awareness among shepherds about the disease, its symptoms and necessary precautions, the doctor added. Dr Amitabh Thakur, Deputy Director o
The WHO chief also warned that climate change is fueling the breeding of mosquitoes, and incidence of dengue has already risen sharply in recent decades, particularly in the Americas
When predicting future estimates of coral disease, the model suggested that the disease prevalence could reach 76.8 per cent in 2100 if temperatures continue to rise
Amyloidosis is a rare disease whose cause is still not found. In May this year, India got its first amyloidosis centre at Amrita Hospital in Kerala
The Centres for Disease Control and Prevention (CDC) reported unusual spikes in cases across the United States last month
Mandaviya, in his address, highlighted the importance of collaborative research in mitigating and responding effectively to global health crises
Even as the wrath of the Covid-19 pandemic begins to wade, the horrors of the medical emergency still seem fresh in the memories
Uttarakhand, Maharashtra and Karnataka lead the way; 1.9 million vaccine doses administered in new cycle
Researchers found that 430 veterans had been diagnosed with Parkinson's, and that their risk was 70 per cent higher than those not exposed
World Liver Day is observed every year on April 19, liver diseases are the tenth most common cause of death in India
On April 17, it is celebrated to raise awareness of Haemophilia and other inherited bleeding disorders
PM Modi launched the TB-Mukt Panchayat initiative, a pan-India rollout of a shorter TB Preventive Treatment (TPT) and a family-centric care model for tuberculosis
Amid the rising number of influenza cases seen in the country, more patients are reporting pneumonia-like conditions and ear fullness, doctors said here on Saturday.