Page 292 - Health Medical Pharma
Crash diets linked to more belly fat, less muscle: Study
If you are planning to take up extreme dieting or crash diets to cut that extra flab, think twice. According to a study, crash dieting would result in more belly fat and less muscle.
'Umbilical cord stem cells may help repair cleft palate'
A technique using umbilical cord blood stem cells could be a promising new approach for repairing cleft palate in infants, scientists say. Performed as part of reconstructive surgery when the infant is a few months old, the stem cell procedure provides good results in growing new bone to close the upper jaw cleft -- and may avoid the need for later bone graft surgery, said Alejandro Garcia Botero from Hospital De San Jose in Colombia. In the study published in The Journal of Craniofacial Surgery, researchers describe the stem cell procedure in an infant with cleft lip and palate, diagnosed by ultrasound before birth. The baby girl had an alveolar cleft, involving an area of bone where teeth are located. Immediately after delivery, a sample of the infant's umbilical cord blood was collected to isolate stem cells, which were processed and frozen to preserve them for later use. Umbilical cord blood is a rich source of various types of stem cells, which have the potential to develop into .
Deep space travel may damage astronauts' gut function
Deep space travel, such as a journey to Mars, can significantly damage the gastrointestinal (GI) tissue of astronauts, and raise the risk of stomach and colon tumours, according to scientists including one of Indian origin. Simulations with animal models that mirror galactic cosmic radiation exposure to astronauts are raising red flags for the researchers at Georgetown University in the US about the health of astronauts. The study, published in the journal PNAS, suggests that deep space bombardment by galactic cosmic radiation (GCR) could significantly damage gastrointestinal (GI) tissue leading to long-term functional alterations. Their previous work has highlighted potential impairment to brain tissue as well as accelerated aging on long space trips due to the effect of energetic heavy ions, which do not affect Earthlings due to the protective global magnetosphere. "Heavy ions such as iron and silicon are damaging because of their greater mass compared to no-mass photons such as ...
Umbilical cord stem cells can help early repair of cleft palate
Researchers have found that a technique using umbilical cord blood stem cells could be a promising new approach for repair of cleft palate in infants.
Dr Reddy's recalls around 70,000 vials of Zoledronic acid injection from US
The US arm of drug firm Dr Reddy's Laboratories is recalling around 70,000 vials of Zoledronic acid injection manufactured by Gland Pharma from the US market, the latest report of the US health regulator has said. Dr Reddy's Laboratories Inc is "recalling 59,468 vials of Zoledronic acid injection, 5mg/100 mL (0.05 mg/mL) 100ml vial," Enforcement Report of the United States Food and Drug Administration (USFDA) said. The company is also recalling 10,530 vials of Zoledronic acid injection, 5 mg/100 mL (0.05 mg/mL) one 100ml single-dose bottle, it added. The vials are being recalled on account of "Out-of-specification result observed for related substance: unknown impurity," the report said. The product was distributed to retailers, distributors, physician officers and medical facilities throughout the United States, it added. The vials were manufactured by Gland Pharma for Dr Reddy's Laboratories, the Enforcement Report said. As per the USFDA "all recalls monitored by FDA are included in
Deep space travel may damage astronaut's gut functions
Exposure to galactic cosmic radiation during deep space travel, such as to Mars, might significantly damage gastrointestinal functions in astronauts, say researchers, led by one of an Indian-origin.
Cataracts linked to higher bone loss, fracture risk: Study
Older adults with cataracts are more likely to be at risk of developing osteoporosis and bone fractures, a study suggests.
Impatient patients turn to online 'buyers club' for new drugs
LONDON (Reuters) - Frustrated by delays in new medicines reaching their own country, a small but growing number of patients are turning to an online broker that bills itself as a legal version of the Dallas Buyers Club.
'Anti-venom against deadly snake bites developed'
Scientists have developed an experimental anti-venom against toxins from the world's most feared venomous snake, the black mamba, which is found in Africa. The findings may lead to a paradigm shift in snakebite treatment, said researchers at Technical University of Denmark (DTU). "The leap forward in our experiments is that we used a biotechnological method to find and then propagate human antibodies in the laboratory to enable use in the treatment of experimental black mamba envenoming," said Andreas Hougaard Laustsen, an associate professor at DTU. "The method we employed can be used to discover human antibodies in the lab by simulating of the human immune system, so we can avoid injecting patients with snake venom to raise antibodies by immunisation," said Laustsen. The antibodies for the experimental black mamba antivenom were discovered using an antibody library containing human antibody genes extracted from white blood cells in donor blood. These genes were inserted into ...
'This algorithm may help find new antibiotics, cancer drugs'
In the search for new antibiotics and cancer drugs, scientists have developed a computer algorithm that reduces the chances of simply rediscovering known compounds. The study, published in the journal Nature Communications, found a new means of searching vast repositories of compounds produced by microbes. Researchers, including those from the Carnegie Mellon University in the US, were able to identify known compounds within the repository and eliminate them from further analysis. They focussed on the unknown variants that might potentially be better or more efficient antibiotics, anticancer drugs or other pharmaceuticals. In just a week, running on 100 computers, the algorithm, called Dereplicator+, identified over 5,000 promising, unknown compounds that merit further investigation, said Hosein Mohimani, an assistant professor at Carnegie Mellon University. In the past, mass spectrometry data repositories have been underused because it was difficult to search through them and because
Diabetes may increase cancer risk: Study
Diabetes can increase the risk of developing a number of cancers, and may reduce the chances of survival in cancer patients, a study has found. Researchers from the Swedish National Diabetes Register (NDR) compared over 450,000 people with type 2 diabetes with more than 2 million matched controls over an average of 7 years. For the most common cancers, individuals with diabetes face a 20 per cent greater risk of developing colorectal cancer and a five per cent higher risk of breast cancer compared with their diabetes-free counterparts. People with diabetes already diagnosed with cancer also fare worse, with a 25 per cent and 29 per cent higher chance of dying following a breast and prostate cancer diagnosis respectively than their peers without diabetes. More than 415 million people are living with diabetes worldwide --equivalent to 1 in 11 of the adult population -- and this figure is expected to rise to 642 million by 2040. Previous research has suggested a link between type 2 ...
Natural compound may help fight ageing: Study
A natural compound found in many fruits and vegetables may help fight ageing by reducing the level of damaged cells in the body, scientists have found. As people age, they accumulate damaged cells which at a certain level go through an ageing process of their own, called cellular senescence, said researchers at the University of Minnesota in the US. The cells also release inflammatory factors that tell the immune system to clear those damaged cells. A younger person's immune system is healthy and is able to clear the damaged cells. However, as people age, they are not cleared as effectively. They begin to accumulate, cause low level inflammation and release enzymes that can degrade the tissue. The study, published in the journal EBioMedicine, found that a natural product, called Fisetin, reduces the level of these damaged cells in the body. The researchers treated mice towards the end of life with this compound and analysed improvement in health and lifespan. "These results suggest ...
Ipca Laboratories acquires 80% stake in Bayshore Pharmaceuticals
Through its wholly owned subsidairy Ipca Pharmaceuticals Inc., USA
Focus: With Hemlibra, Roche seeks to break into tight hemophilia circle
ZURICH (Reuters) - Swiss drugmaker Roche is breaking into hemophilia A treatment, a $10 billion global market dominated by rivals who have cultivated close ties to sufferers of the genetic bleeding disorder.
Dr Reddy's Lab rises after sale of Cloderm Cream
Dr Reddy's Laboratories rose 0.41% to Rs 2,521.45 at 09:32 IST on BSE after the company announced the sale of Cloderm Cream to EPI Health, LLC.
Merck Ltd Spurts 3%
Merck Ltd has lost 17.85% over last one month compared to 5.24% fall in S&P BSE Healthcare and 5.11% drop in the SENSEX
Women's health deteriorate more rapidly than men prior to diabetes
A new study has found that prior to the onset of type 2 diabetes (T2D), women with versus without prediabetes experience significantly have larger adverse differences in their cardiometabolic health than men. However, the mechanisms responsible for these sex differences remain a mystery.The research, conducted by the Maastricht University Medical Centre, aimed to evaluate sex-related differences in cardiovascular risk factor levels, both before and after the onset of T2D.T2D is known to reduce or even reverse the protective effect of being female on the risk of developing cardiovascular disease. The metabolic changes that eventually lead to T2D can precede the development of hyperglycemia (caused by poorly controlled blood glucose levels) by years or even decades. Despite this, there has been a little investigation into whether women suffer a relatively worse cardiometabolic risk profile before developing the disease.The authors analysed a population-based cohort of individuals aged ..
Pentagon finds poisonous mail sent to Mattis, chief of naval operations
Two pieces of mail tested positive for ricin by the Pentagon mail facility were addressed to US Defence Secretary Jim Mattis and Chief of Naval Operations Admiral John Richardson, the Defense News reported.
'Diabetes increases cancer risk'
Diabetics are at an increased risk of cancer, warns a study. It also suggests that diabetes is linked with poorer survival following a cancer diagnosis.For the most common cancers, individuals with diabetes face a 20 percent greater risk of developing colorectal cancer and a five percent higher risk of breast cancer compared with their diabetes-free counterparts.People with diabetes already diagnosed with cancer also fare worse, with a 25 percent and 29 percent higher chance of dying following a breast and prostate cancer diagnosis (respectively) than their peers without diabetes.Hulda Hrund Bjornsdottir, from the Swedish National Diabetes Register (NDR), Sweden, and colleagues found that diabetes was associated with 11 out of the 12 specific types of cancer investigated in the study.Diabetes was clearly linked with higher risk of cancers of the liver (people with diabetes were 231 percent more likely to be diagnosed with liver cancer than those without a history of diabetes over the .
Govt super speciality hospital inaugurated in Raipur
Chhattisgarh Chief Minister Raman Singh inaugurated the state government's first super speciality hospital here Tuesday. Spread over 13.8 acres, Dau Kalyan Singh Super Speciality Hospital has been built at a cost of Rs 140 crore in the old Mantralaya building at Shastri Chowk. "Chhattisgarh has stepped into a new age of health and medical services sector. The super speciality hospital will provide best quality treatment at affordable price to people," Singh said at the opening ceremony Tuesday evening. A post-graduate institute and a research centre have also been set up in the hospital building. A health department official said that before the formation of the state in 2000, a hospital in the name of Danveer Dau Kalyan Singh ran from these premises. Afterwards the building housed the new state's secretariat. However, the Mantralaya was shifted to Naya Raipur in 2012, and the government later decided to set up a super speciality hospital in this building. The new ...