Page 371 - Health Medical Pharma
Indivior: U.S. court rules against generic rival's appeal
(Reuters) - Indivior Plc notched a legal victory on Tuesday after a U.S. court reaffirmed that a generic rival could not re-launch cheaper versions of the British drugmaker's best-selling opioid addiction treatment in the United States.
Scientists develop preliminary universal influenza vaccine
Scientists have developed a new nanoparticle vaccine that could effectively protect mice against influenza A virus, providing a promising approach for developing universal vaccines for the infectious disease.
Anti-bodies that fight Ebola viruses are now a reality
Finally, anti-bodies to three major Ebola viruses have now been developed.Researchers at Vanderbilt University Medical Center are a step closer to developing a broadly effective antibody treatment against these viruses that cause the lethal disease in humans.Researchers found that the isolation of two potent monoclonal antibodies from human survivors of Ebola virus disease in cell culture studies efficiently neutralized the Zaire, Sudan and Bundibugyo Ebola viruses.The antibodies, EBOV-515 and EBOV-520, also showed the capacity to protect against infection by these viruses in animal models.Researchers said further study is needed as these antibodies could lead to development of injectable antibody "cocktails" for people at high risk of being infected by Ebola viruses.The hope is that the antibodies would work like heat-seeking missiles that would seek out and destroy the viruses before they can wreak havoc in the body."Our team was very excited to discover these new antibodies that ...
Inactivity amongst older people leads to diabetes
Inactivity for two straight weeks amongst older overweight people increases the risk of Type 2 diabetes.Not only did an abrupt, brief period of inactivity hasten the onset of the disease and elevate blood sugar levels among pre-diabetic patients, but researchers reported that some study participants did not fully recover when they returned to normal activity for two weeks."We expected to find that the study participants would become diabetic, but we were surprised to see that they didn't revert back to their healthier state when they returned to normal activity," said a lead researcher Chris McGlory.People who participated in the research were asked to reduce their daily steps to no more than 1000 times per day, which is the equivalent of being housebound.Their steps and activity which were measured using pedometers and specialized activity monitors, while researchers tested their blood sugar levels and took blood samples during the two-week period.The results implied that seniors who
Hair loss gene is key to improved cancer immunotherapy
Harnessing the gene behind hair loss could help improve cancer immunotherapy.A study by Columbia University Irving Medical Center researchers confirmed the possibility."While immunotherapies have shown great promise in cancer, most patients do not benefit from these treatments because their tumours are able to evade the immune system," said a lead researcher, Angela M. Christiano."But one way around this obstacle is to harness genes that cause the recruitment of T cells in autoimmune disease and use them to attract T cells to kill tumours. In this study, we showed that a gene that recruits T cells in alopecia areata- a condition in which immune cells attack and destroy hair cells--is turned off in various types of cancer, protecting them from the immune system. But if we turn that gene back on, we can make those cancers vulnerable to the immune response," he added.The study began with the recognition that auto-immune diseases and cancer represent opposite ends of the immune signalling
Demi Lovato may be suffering from overdose complication
Singer Demi Lovato is still hospitalised here six days after a suspected drug overdose and is reportedly suffering from complications.
3 in 5 babies not breastfed in first hour of life
According to United Nations Children's Fund (UNICEF) and World Health Organization (WHO), around 78 million babies or three in every five are not breastfed within the first hour of the birth, putting them at a higher risk of death and disease and making them less likely to continue breastfeeding.Most of these babies are born in low- and middle-income countries.According to the report, newborns who breastfeed in the first hour of life are significantly more likely to survive. Even a delay of a few hours after birth could pose life-threatening consequences.It should be noted that skin-to-skin contact along with suckling at the breast stimulates the mother's production of breast milk, including colostrum, also called the baby's 'first vaccine', which is extremely rich in nutrients and antibodies.UNICEF Executive Director Henrietta H. Fore said, "When it comes to the start of breastfeeding, timing is everything. In many countries, it can even be a matter of life or death," adding, "Yet ...
Karunanidhi's health continues to be same: Stalin
There has been no change in the health condition of DMK President M. Karunanidhi from what the hospital had said on Sunday, said his son and party leader M.K. Stalin said on Monday.
Bihar hospital under knee-deep water cleared of waterlogging
The state-run Nalanda Medical College and Hospital (NMCH), whose ICU and wards were under knee-deep water due to rains in which fish swam, was cleared of the waterlogging today. Water has been pumped out and all the wards were cleaned and bleaching powder sprinkled today, NMCH Superintendent Chandrashekhar told PTI today. Doctors, nurses and patients had to wade through knee-deep water and fish swam in the ICU of the NMCH yesterday on account of rain water deposit. Water had entered into the Intensive Care Unit (ICU) of the medicine department forcing shifting of patients to Surgerry wing emergency unit. Built in 1970, the hospital which is located in a low lying area, saw water entering into its various wards due to the heavy showers on July 28-29. Television channels had beamed how the hospital's ICU turned an aquarium with fish swimming inside. The Hospital Superindent said that the patients shifted from ICU of medicine department to that in the Surgery wing would ...
India can be global healthcare destination: Apollo Chairman
Leveraging technologies like artificial intelligence (AI) and telemedicine, best healthcare for people can be delivered even in remote areas of the country and make India the global healthcare destination, said Prathap C. Reddy, Chairman of Apollo Hospitals on Monday.
India can become global healthcare destination: Apollo's Prathap Reddy
Leveraging technologies like artificial intelligence (AI) and telemedicine, best healthcare for people can be delivered even in remote areas of the country and make India the global healthcare destination, said Prathap C. Reddy, Chairman of Apollo Hospitals on Monday.
Japan human trial tests iPS cell treatment for Parkinson's
Japanese researchers today announced the first human trial using a kind of stem cell to treat Parkinson's disease, building on earlier animal trials. The research team at Kyoto University plans to inject five million induced Pluripotent Stem (iPS) cells -- which have the potential to develop into any cell in the body -- into patient brains, the university said in a press release. The iPS cells from healthy donors will be developed into dopamine-producing brain cells, which are no longer present in people with Parkinson's disease. Parkinson's disease is a chronic, degenerative neurological disorder that affects the body's motor system, often causing shaking and other difficulties in movement. Worldwide, about 10 million people have the illness, according to the Parkinson's Disease Foundation. Currently available therapies "improve symptoms without slowing or halting the disease progression," the foundation says. But the new research aims to actively reverse the disease. The clinical ..
Morepen Lab shares jump 12 pc on USFDA nod for bulk drug units in HP
Shares of Morepen Laboratories today surged 12 per cent after the company received approval from the US health regulator for two bulk drug facilities in Himachal Pradesh. The stock soared 11.77 per cent to settle at Rs 35.60 on the BSE. During the day, it jumped 16.48 per cent to Rs 37.10. On the NSE, shares of the company rose sharply by 11.93 per cent to end at Rs 35.65. In terms of equity volume, 10.79 lakh shares of the company were traded on the BSE and over 65 lakh shares changed hands on the NSE during the day. Morepen Laboratories today said it has received approval from the US health regulator for two bulk drug facilities in Himachal Pradesh manufacturing Atorvastatin Calcium and Montelukast Sodium, respectively. While the Baddi facility has got US Food and Drug Administration (USFDA) nod to manufacture cholesterol reducing bulk drug Atorvastatin Calcium, the Masulkhana facility has received approval for manufacturing anti-asthma bulk drug Montelukast Sodium, the company said
Patient who had been in Congo tests negative for Ebola virus
Colorado health officials said a patient who became ill after visiting the Congo has tested negative for the Ebola virus. The man arrived at Denver Health Medical Centre yesterday and was placed in an isolation unit as a precaution. Three people who also had contact with the patient were also isolated and the vehicle that transported the patient was quarantined. The region of the Congo where the man visited has not had an Ebola case for more than 45 days. Denver Health chief medical officer Connie Price says the symptoms can mimic a lot of common illnesses. The patient is in fair condition.
Being overweight may up heart disease risk: Study
Being overweight may cause higher blood pressure and thicken heart muscle, setting the stage for heart disease later in life, a study has found. The research, published in the journal Circulation, is the first to explore if higher body mass index (BMI) - a weight-for-height index - results in adverse effects on the cardiovascular system in young adults. "Our results support efforts to reduce body mass index to within a normal, healthy range from a young age to prevent later heart disease," said Kaitlin H Wade from the University of Bristol Medical School in the UK. Researchers used data on several thousand healthy 17-year-olds and 21-year-olds participating in an ongoing study since birth in Bristol, UK. The findings suggest that higher BMI caused higher systolic (top number) and diastolic (bottom number) blood pressure. It also caused enlargement of the left ventricle, the heart's main pumping chamber, the researchers said. "Thickening of vessel walls is widely considered to be the ..
Scientists discover new shape - the 'scutoid'
Epithelial cells, which cover the surfaces of many organs, adopt a previously undescribed geometric shape - the scutoid - so that the tissue can curve, scientists have found. The epithelial cells adopt this form which looks like 'twisted prisms', according to the research published in the journal Nature Communications. These new and beautiful shapes are the solution that nature has found to fold and curve the epithelia, which lines the outer surfaces of organs, researchers said. "The epithelial cells are the construction blocks with which an organism is formed. They are like 'pieces of Tente or Lego from which animals are made,'" said Luisma Escudero from the University of Seville in Spain. The epithelia form structures with multiple functions like forming a barrier against infections or absorbing nutrients. During the development of an embryo, it changes from a simple structure formed from only a handful of cells to an animal with very complex organs. "This process doesn't only occur
Ex-servicemen rally held at Doda
The Rashtriya Rifles, a unit of the Indian Army, organised a mega ex-servicemen rally in Doda town of Bhadarwah district in Jammu and Kashmir, an Army officer said today. The rally, which was organised by the 4 Rashtriya Rifles (RR), was attended by over 100 ex-servicemen, war veterans, disabled soldiers, war widows and other family members hailing from Bhadarwah, Bhalessa, Chirala and Marmat areas of Doda district, the officer said. The meet was held to provide a platform for registration of grievances and for their immediate redressal. Issues related to pension, health care, re-employment, among many others were taken up at the meet, he said. Commanding Officer Colonel D D Pandey chaired the event. Later, officers of the battalion and president of District Sainik Board interacted with the veterans and briefed them about the various schemes. Speaking on the occasion, the commanding officer said ex-servicemen remain a part of the Army and are an extremely important constituent of ...
Higher BMI in young adults may up CVD risk
Being overweight as a young adult may cause higher blood pressure and thicken heart muscle, setting the stage for cardiovascular (CVD) disease in later life, a new study has found.
Football can help boost bone health in elderly with prediabetes
Playing football can boost heart and bone health in untrained middle-aged and elderly people with prediabetes, a study has found. Researchers from University of Southern Denmark and the University of the Faroe Islands showed the positive effects of football on the cardiovascular and metabolic health profile. "Individuals with prediabetes and type 2 diabetes have a higher prevalence of osteopenia and bone fractures, so it is essential to develop treatment protocols for them," said Magni Mohr, an associate professor at the University of Southern Denmark. "Our results show that football and dietary guidance are indeed an effective cocktail for improving bone health," said Mohr. "The football group derived significant positive effects in the legs and clinically important femoral sites emphasising that football is effective osteogenic training for this participant group," he said. DXA scans were used to evaluate the initial bone health of the participants as well as the training-induced ...
BIZ-TL-DR REDDYS
Dr Reddy's Laboratories has filed a petition in the US Court of Appeals for the Federal Circuit against the preliminary injunction imposed by another US court preventing the Indian drug-maker from selling the generic Suboxone sublingual film in America. Suboxone (buprenorphine and naloxone) sublingual film (applied under the tongue) is meant for the treatment of opioid dependence/addiction. The US Court of Appeals , which said it may hear the petition in the first week of October, had 'granted-in-part' themotion to expeditethe appeal of Dr Reddy's. Based ona petition of Indivior, a specialty pharmaceuticals business listed on the London Stock Exchange, the US court for the district of New Jersey, had, on July 13,granted the preliminary injunction on the launch of Suboxone by Dr Reddy's which has appealed against the ruling. Indiviorsaid itwould continue to defend its patent rights to the Suboxonefilm, including opposing Dr Reddy's appeal. Suboxone recorded sales of ...