Page 96 - Health Medical Pharma
Breast cancer patients unresponsive to therapy show epigenetic differences: Study
Breast cancer patients who do not respond to targeted therapy show epigenetic differences, a new study has revealed.According to the study, presented at the Experimental Biology 2019, breast cancer patients who don't respond to targeted therapy have different patterns of epigenetic modifications than patients who do respond.Epigenetic modifications change gene expression without altering the DNA's genetic code."Our study could contribute to new ways to predict who might not respond to targeted therapy.It could also lead to ways to identify patients who need a closer clinical follow-up because they are more prone to experience breast cancer recurrence," said Daniela Furrer, a researcher.Targeted cancer therapies use drugs to block molecules in cells that cause them to grow out of control. The therapy specifically targets cancer cells, unlike chemotherapy, which kills all quickly growing cells whether they are cancerous or not. Although the development of targeted therapies has ...
Uttarakhand: 2 apprehended for injuring elephant calf
Two men have been apprehended after the truck they were travelling in allegedly hit an elephant calf on Saturday night in Lachhiwala forest range near Doiwala.The truck driver and conductor have been apprehended by the forest department.The male calf, which is around three-and-a-half years old is currently being given medical treatment.
IoT in healthcare at serious cyber attack risk
While the healthcare industry is rapidly adopting new-age technologies such as the Internet of Things (IoT) and Artificial Intelligence (AI) to improve access and outcomes especially in the rural areas, companies must ensure that the technology acts with responsibility and transparency, say experts.
Spicy compound from chilli peppers could reduce spread of lung cancer, shows study
Now, there is a reason to start liking the heat of chillies. A new study has suggested that the compound responsible for chilli peppers' heat could help slow the spread of lung cancer.The research was presented at the American Society for Investigative Pathology annual meeting during the 2019 Experimental Biology meeting.Lung cancer is the leading cause of cancer death for both men and women. Most cancer-related deaths occur when cancer spreads to distant sites, a process called metastasis."Lung cancer and other cancers commonly metastasise to secondary locations like the brain, liver or bone, making them difficult to treat. Our study suggests that the natural compound capsaicin from chilli peppers could represent a novel therapy to combat metastasis in lung cancer patients," said Jamie Friedman.In experiments involving three lines of cultured human non-small cell lung cancer cells, the researchers observed that capsaicin inhibited invasion, the first step of the metastatic ...
Poverty leaves a mark on genes: Study
Poverty can leave a lasting imprint in our DNA, say scientists who have found that low socioeconomic status is linked to changes in over 1,500 genes. Previous research has shown that socioeconomic status (SES) is a powerful determinant of human health and disease, and social inequality is a ubiquitous stressor for human populations globally. Lower educational attainment and/or income predict increased risk for heart disease, diabetes, many cancers and infectious diseases, for example. Furthermore, lower SES is associated with physiological processes that contribute to the development of disease, including chronic inflammation, insulin resistance and cortisol dysregulation. Scientists from Northwestern University in the US found evidence that poverty can become embedded across wide swaths of the genome. They discovered that lower socioeconomic status is associated with levels of DNA methylation (DNAm) -- a key epigenetic mark that has the potential to shape gene expression -- at more ..
Poor sleep linked to genetics: Study
Suffering from sleep disorder? Blame genetics. A new study has found several parts of our genetic code that could be responsible for poor sleep.
Treating preeclampsia with sildenafil may protect offspring's cardiovascular health: Study
A new research conducted in rats has found that treating preeclampsia with sildenafil citrate (Viagra) may help protect the cardiovascular health of the offspring.The research was presented at the American Physiological Society's annual meeting, Experimental Biology 2019.An estimated six to 15 million people in the United States are children born of a pregnancy complicated by preeclampsia.Preeclampsia occurs when women with otherwise normal blood pressure experience elevated blood pressure during pregnancy.Children of women with preeclampsia during pregnancy have higher blood pressure during childhood and almost double the risk of stroke later in life."The ultimate goal of our work is to improve the long-term health of women and children affected by preeclampsia," said Hannah Turbeville, a researcher."There are limited guidelines for addressing the health risks to these groups, and we hope not only to bring attention to these risks but also to propel research forward that will inform .
Look-out circular against Raman Singh's son-in-law
Dr Puneet Gupta, son-in-law of former Chhattisgarh Chief Minister Raman Singh, continues to evade the police almost two weeks since he was expected to present himself before them.
New study explains why heart failure patients suffer depression
Patients related to heart diseases often experience difficulty in thinking and likely suffer depression, a new study explains. The study published in the Journal 'Scientific Reports', also points out prevention for the same."Neurosurgeons always look in the brain; cardiologists always look in the heart. This new study looked at both," said Martino, working in the field of circadian medicine.This study is first of its kind done on mice that test how cognition and mood are regulated by body clock and how pertinent brain regions are impaired in heart failure."Human patients with heart failure often have neurological conditions such as cognitive impairment and depression," said Martino.For this new study, the researchers compared normal mice with mice carrying a mutation in their circadian mechanism (called "clock mice"). They found that the mutation affected the structure of neurons in brain areas important for cognition and mood.The results show that the circadian mechanism influences ..
Study finds an innovative and non-invasive way to diagnose Alzheimer's disease
A new study published in the journal PLOS ONE has revealed that Alzheimer disease can now be diagnosed in a new and non-invasive way.Reduced blood capillaries in the back of the eye may be a new and non-invasive way to diagnose early cognitive impairment, the precursor to Alzheimer's disease, according to the study.Scientists detected these vascular changes in the human eye non-invasively, with an infrared camera and without the need for dyes or expensive MRI scanners.The back of the eye is optically accessible by a new type of technology (OCT angiography) that can quantify capillary changes in great detail and with unparalleled resolution, making the eye an ideal mirror for what is going on in the brain."Once our results are validated, this approach could potentially provide an additional type of biomarker to identify individuals at high risk of progressing towards Alzheimer's," said Dr Amani Fawzi, a researcher."These individuals can then be followed more closely and could be prime .
Add chokeberries in porridge to help boost health
While bananas and blueberries have been commonly used in porridge, a new study suggests that adding chokeberries, called 'the healthiest fruit in the world', can help boost health.
Stop smoking cigarettes before they make you blind
Do you smoke cigarettes? Think twice before taking another drag as it may not only damage your heart or lungs but can also make you blind, experts say.
Just one drink daily can raise stroke risk
While it is known that excess drinking is harmful for health, a new study suggests that even consuming one or two alcoholic drinks a day can raise stroke risks, challenging previous claims.
Research finds anti-inflammatory drugs futile against the prevention of Alzheimer's disease
Nonsteroidal anti-inflammatory drugs (NSAID) are ineffective for the prevention of Alzheimer's disease, reveals new research published in the medical journal of the American Academy of Neurology.For decades, researchers have known that inflammation accompanies Alzheimer's disease (AD) brain lesions. Several earlier studies suggested that 'super-aspirins' or Nonsteroidal anti-inflammatory drugs (NSAID) could help avoid the disease.However, clinical trials showed that NSAIDs don't help patients who already have AD symptoms. Doctors wondered whether these drugs could still be helpful to people who were at risk of developing the disease, but weren't yet showing symptoms.To test this hypothesis, researchers developed a new approach to AD prevention trials and used it to test whether the common NSAID naproxen could indeed stop the disease in its tracks before people developed AD symptoms. But, the results were not encouraging."To give the NSAID story one more chance to end well, we enrolled
Protein complex clears potential traffic jams in RNA production, finds research
A new research has found that a protein complex plays a key role in clearing potential traffic jams in the production of RNA.The research was published in the journal Genes & Development."The 'Ccr4-Not' complex is involved in nearly every step of this process from start to finish. Our new research shows that this complex has an additional function that helps maintain normal cellular function when something goes wrong during transcription," said Joseph C. Reese, a researcher.During the transcription of RNA from DNA, RNAPII, itself a large complex made up of multiple protein subunits, travels along the strand of DNA reading the ATCG sequence and producing a complementary strand of RNA.If the RNAPII encounters DNA damage, which can be caused by UV radiation and other sources, it can become stuck and prevent trailing polymerases from completing transcription of the gene, similar to how a stalled car prevents traffic behind it from flowing.If this jam cannot be cleared, multiple ...
Healthy food trends for this World Health Day
Good health is your best friend and if you are the one who believes in it, it's time to pick up the pace and get in touch with healthy food trends that are gripping the food community across the globe this World Health Day.With quality becoming a rage these days, more and more food enthusiasts are catching up on the trend of eating right and healthy. Recently, the US Time magazine's special edition issue on "100 Healthiest Foods to Satisfy Your Hunger" included walnuts and named them the "single healthiest weekday work snack". Likewise, here are some upcoming trends that our experts believe to be hot on the menu!Health rules the tableWith more and more people leaning towards healthy living, power-packed nutritious meals are going to be a hit this year. You can add to your platter ingredients that are not only appealing to your taste buds but also good for your body. Rich in essential nutrients like fibre, minerals, and vitamins, superfoods like California walnuts add the goodness of ..
In letter to govt, NGO highlights need for policy on vaping products
An NGO has written to the Prime Minister's Office highlighting the need for a regulatory framework for vaping products, so that they can be used as an alternative to combustible tobacco products like cigarettes. The Heart Care Foundation of India also marked the letter to the Ministry of Health and state health departments on policies and regulations of vaping products, including e-cigarettes, based on a consensus statement signed by leading medical practitioners, which is scheduled to be published in the April edition of Indian Journal of Clinical Practice. The consensus statement shared on the Indian Journal of Clinical Practice website highlights the need for a regulatory framework for vaping products, which allow adults to access quality-controlled products in their efforts to stop the use of combustible smoking with the objective to reduce harm. The letter urges the government to ensure that the policy for vaping products addresses issues like making such products available to ...
Congo: Over 600 dead in Ebola outbreak, second deadliest since 2014
In the second deadliest Ebola outbreak since 2014, that killed 11,000 in West Africa, 629 people have lost their lives in the Democratic Republic of Congo. According to UN Secretary General spokesman, Stephane Dujarric, about 1,041 new cases of Ebola have been confirmed in the region."The World Health Organization (WHO) says a marked increase in the number of Ebola cases in that country took place this week, highlighting the difficult environment and the multitude of challenges confronting the response to the outbreak," Dujarric said on Friday, reports Xinhua."Some 338 patients who received care at Ebola treatment centres have now been discharged," the spokesman added.The WHO has said that raids on Ebola treatment centres by "non-state actors" have deterred locals from seeking aid, including getting the vaccination for high-risk subjects.However, there are a few positive outcomes from the mechanisms put in place by WHO. "The agency reports that a recent shift in the response strategy .
YSRCP announces free healthcare for poor, middle class
YSR Congress Party chief YS Jagan Mohan Reddy on Friday announced Universal Healthcare Card scheme to provide free healthcare access to poor and middle-class people.The announcement was made by Jagan during a public rally at Kuppam in Chittoor district, less than a week before polling is scheduled to begin in the state.Under the healthcare scheme, any individual with an annual income of up to Rs 5,00,000 can avail medical services free of cost. Taking YSR's vision of Arogyasri forward, the universal health cards will be applicable for any medical expense over Rs. 1,000.The Universal Health Card scheme will be personally monitored by Jagan Reddy.Simultaneous elections will be held in Andhra Pradesh for 25 Lok Sabha seats and 175 Assembly seats. The results will be declared on May 23.
Yoga gaining popularity across world : Venkaiah Naidu
Vice President M Venkaiah Naidu Friday said yoga is gaining popularity across the world as it helps in reducing mental stress and in treatment of several serious ailments. He also said non-communicable diseases were a "deeply disturbing trend" and called upon the medical fraternity to educate the people on the dangers of sedentary lifestyles. Naidu was addressing the annual meeting of the National Interventional Council (NIC) of the Cardiological Society of India at the Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS). Highlighting the importance of yoga, Naidu recalled an incident when a man came ups to him and said that though yoga was okay, he had a problem doing surya namaskar. "I understood his problem and told him even if he is not able to do surya namaskar ...yet he should do yoga as it is very important for mental, physical and spiritual health... it is gaining popularity the world over and yoga centres are being opened, but there are some who link it to ...