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Genes may decide how your heart responds to exercise: Study

Press Trust of India  |  Toronto 

Your genes can determine how your rate and respond to -- and may act as an early warning of future cardiovascular problems, a study has found.

Until now it has not been known why the response to varies between different people, researchers said.

The study, published in The Journal of Physiology, found that genetic differences in receptors found in skeletal muscles can contribute to this different response.

Receptors are groups of specialised cells that detect changes in the environment and cause some kind of response.

The scientists identified that the presence of two common genetic mutations in receptors found in skeletal muscle led to higher during compared to people who did not have them, particularly in men.

The study, conducted by researchers at the in Canada, involved measuring rate and of 200 healthy young men and women before and during a handgrip exercise, plus analysing their DNA for genetic risk factors.

The effect of genetic variants in the skeletal muscle receptors was significant, researchers said.

"This research suggests the presence of these receptors can contribute to larger blood pressure responses during exercise -- a risk factor for future problems with the or blood vessels," said Philip J Millar, an of the study.

"It is important to examine why we saw this difference mainly in men, and to understand the specific mechanisms behind how these genetic variants influence their heart rate and blood pressure responses to exercise," Millar said.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Wed, September 12 2018. 16:00 IST
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