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Smoking, alcohol consumption during pregnancy may lead to congenital deformities of face

Press Trust of India  |  New Delhi 

Smoking, alcohol consumption, exposure to chulha smoke or passive smoking, over-medication and exposure during first few weeks of along with may lead to of the face such as lip and palate anomaly, according to a study by AIIMS.

lip or palate is a condition when the two sides of the lip, developing in an unborn baby, do not completely fuse together. It affects weight speech and chewing habit of a child and leads to abnormal arrangement of teeth, poor jaw relations and facial aesthetic.

and palate anomaly constitute nearly one-third of all congenital malformations of the craniofacial region with an average worldwide incidence of 1 in 700.

Its incidence in Asian population is reported to be around 1.7 per 1,000 live births or higher.

In India, even though a national epidemiological data is not available, many studies from different parts of the country have reported a variation in the incidence of cleft anomaly.

Based on rough estimates, it is suggested that approximately 35,000 new-born cleft patients are added every year to the Indian population.

The study, initiated by (CDER) at All Institute of Medical Sciences since 2010, was conducted in three phases: pre-pilot,

The phase was conducted between 2010 and 2012. It aimed at developing comprehensive protocols for recording the history, investigations on dental anomalies, hearing defects and evaluation of speech-related problems in patients with

"The idea was to have a uniformity in the procedure of collecting the patients' records," said O P Kharbanda, of CDER and of the project.

During the pilot phase (2012-2014), data of 164 cases with and palate anomaly were recorded from three high-volume cleft care centres in and National Capital Region, involving two public funded hospitals AIIMS and Safdarjung and one private hospital Medanta-The Medicity in Gurgaon.

"It revealed that patients suffering from this had high treatment need with an immediate need to devise strategies to improve the delivery of quality care," said.

Currently, the multi-centric phase is underway in New Delhi, Hyderabad, and

"In our study, we also evaluated a few risk factors including maternal and alcohol consumption, intake of drugs during the first trimester of and exposure to smoke during the same time by the use of chulha at home or due to passive

"We also took into account the history in drug intake and exposure in the first trimester of and it was concluded that all these risk factors may be related to increased incidence of cleft in the progeny," said.

The government's Rashtriya Bal Swasthya Karyakram has identified and palate as one of the which are recorded under the programme.

A web-based recording system, "IndiCleft" tool, has been developed with the help of The Balram Bhargava, of ICMR, will launch the "IndiCleft" tool on February 14.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Sun, February 10 2019. 13:15 IST