Superintendent of Police of Quaidabad area, Mubarak Shah, was targeted by the gunmen in Quetta, the provincial capital, while he was patrolling in the area with his team.
Inspector General of Police in Balochistan Abdul Razzak Cheema confirmed the attack on Shah.
"Shah was injured and later died in the hospital while three police personnel died on the spot," he said.
Another policeman was injured and was being treated.
"It appears to be another targeted attack on policemen," Cheema said.
Prime Minister Nawaz Sharif in a tweet strongly condemned the attack.
The incident comes days after District Police Officer of Qilla Abdullah, his security guard and driver were killed and over 10 other people, including five police personnel, were injured in a suicide blast in the border town of Chaman on Monday.
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)