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Cinnamon oil may help prevent superbug infections: Study

Press Trust of India  |  Melbourne 

Cinnamon essential could play a key role in preventing from that are resistant to the most potent antibiotics, according to a study.

Researchers from in Australia investigated cinnamaldehyde, a major component of cinnamon essential

They found that it inhibited the development of biofilm, a sticky film of - like the plaque that forms on teeth - that can cause persistent infections, which resist even the most potent

There is an urgent need to develop alternatives to to treat chronic biofilm-mediated infections, such as may occur with urinary and artificial joints, said

"Though many previous studies have reported antimicrobial activity of cinnamon essential oil, it is not widely used in the pharmaceutical industry," Topa said.

"We aimed to search for the molecular activity of this oil, focusing on its major component, cinnamaldehyde. This is the compound that gives cinnamon its flavour," she said.

Rather than killing the bacteria, Topa was looking to modify the behaviour of by disrupting bacterial communication to prevent biofilm formation.

"We hypothesised that using natural antimicrobials, such as essential oils, might interfere in biofilm formation. Thus, we focused on the impact of different concentrations of cinnamaldehyde in different biofilm development stages," Topa said.

She tested the effect of different concentrations of cinnamaldehyde on biofilms formed from the pathogenic aeruginosa of bacteria.

Topa found that a sub-lethal concentration of cinnamaldehyde controlled the dispersion of aeruginosa and the development of biofilm.

"Humans have a long history of using to treat infections, and there is a renewed focus on such antimicrobial compounds. may offer a promising solution to this problem," Topa said.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Fri, July 13 2018. 15:35 IST
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