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High-fat diet in elderly linked to heart disease, diabetes

IANS  |  London 

Elderly people, who consume a high-diet rich in Omega-6 fatty acids, could be at risk of developing issues ranging from to heart failure, researchers, including one Indian-origin, said in a study.

The study conducted on a mice model showed that a calorie-dense, obesity-generating diet in ageing mice disrupted the composition of the gut microbiome.

Young mice, who were fed an obesity-generating diet were able to resolve after a heart attack, even though their gut microflora had already been altered by the diet.

In contrast, in aged mice fed the obesity-generating diet, the triggered nonresolving -- associated with

The study, published in FASEB Journal, investigated how ageing and omega 6-enriched diet impact microflora in the gut, the structure and function of the spleen (abdominal organ), and a subsequent immune response to

"This study highlights that diet and age are critical factors that have differential impact with age, and it highlights the spleen and heart as an inter-organ communication system with the immune defence system," said Ganesh Halade, at the University of

The team found that obesity-generating diet increased the proportion of neutrophils in the blood of aged-mice.

Higher neutrophil counts means that you have an or are under a lot of stress.

The obesity-generating diet in eldery also led to in mice spleens.

The spleen, a secondary immune organ, is a known reservoir for leukocytes that move to the heart to begin tissue repair and help resolve in case of an

--IANS

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(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Sun, March 03 2019. 11:38 IST
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