Electing to bat after winning the toss, Pakistan were restricted to 72 for seven in the allotted 20 overs at the Kinrara Academy Oval.
Left-arm spinner Ekta Bisht was the most successful India bowler, claiming impressive figures of 3/14 in her four-over spell. The others chipped in with a scalp apiece, although pace spearhead Jhulan Goswami went wicket-less surprisingly.
Bisht was named Player of the Match.
Chasing a meagre target, India completed the task with as many as 23 balls to spare.
India were off to a disastrous start as they lost Raj and Sharma with just five runs on the board in the third over, but the low target allowed them the liberty of taking things easy.
The duo of Mandhana and Harmanpreet then added 65 runs for the third wicket, a recovery act that powered the team to within striking distance of another victory.
Even as Mandhana got out with three runs for win, Harmanpreet was there to guide her side home.
Earlier, Pakistan's decision to bat did not yield the desired result as they lost wicket at regular intervals, and were stopped at 72.
Sana Mir, one of the most well-know names of Pakistan women's cricket, top-scored for the side with 20, but she consumed as many as 38 balls.
Opener Nahida Khan (18) was the only other Pakistan batswoman to reach double digit.
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