Page 2 - Bacterial Infections

Rare flesh-eating bacteria that can kill in two days spreads in Japan

At the current rate of infections, the number of cases in Japan could reach 2,500 this year, with a 'terrifying' mortality rate of 30%

Lupin recalls 51k bottles of generic drug due to defective containers in US

Drug firm Lupin is recalling over 51,000 bottles of a generic antibiotic medication in the US market due to a "defective container", according to the American health regulator. The US-based arm of the drug maker is recalling 51,006 bottles of Cefdinir for Oral Suspension (250 mg/5 mL) due to "defective container: lack of seal integrity," US Food and Drug Administration (USFDA) said in its latest Enforcement Report. Cefrine Oral Suspension is indicated for the treatment of a range of bacterial infections. The affected lot has been manufactured at Lupin's Mandideep-based plant and marketed in the US by Baltimore-based Lupin Pharmaceuticals, Inc, it said. The drug maker initiated the Class II nationwide (US) voluntary recall on May 8 this year. As per the USFDA, a Class II recall is initiated in a situation in which the use of, or exposure to, a violative product may cause temporary or medically reversible adverse health consequences or where the probability of serious adverse health

Experts flag need to stop OTC sale of antibiotics, spread awareness

The study adds that an estimated 7.7 million die in LMICs due to bacterial infections, of which almost five million deaths are due to AMR bacteria

Dr Reddy's Laboratories launches generic anti-bacterial medication in US

Dr Reddy's Laboratories on Friday said it has launched a generic medication, used to treat a wide variety of bacterial infections, in the US market. The company has launched Doxycycline Capsules (40 mg) in the US market, the Hyderabad-based drug maker said in a statement. The company's product is a therapeutic generic equivalent of Oracea capsules (40 mg) approved by the US Food and Drug Administration (USFDA). Shares of the company on Friday ended 0.71 per cent up at Rs 6,332.85 apiece on the BSE.

Lupin gets USFDA nod to market a generic drug to treat bacterial infections

Drug maker Lupin on Friday said it has received approval from the US health regulator to market a generic medication to treat bacterial infections, in America. The company has received approval from the USFDA for Doxycycline for Injection USP, the Mumbai-based drug maker said in a statement. The company's product is the generic equivalent of Pfizer Inc's Vibramycin for injection, it added. The product will be manufactured at its Nagpur facility, Lupin said. Doxycycline for Injection USP is indicated to reduce the development of drug-resistant bacteria. As per the IQVIA MAT January 2024 data, Doxycycline for Injection USP had estimated annual sales of USD 47 million in the US market.

Swift action must to stop 'silent pandemic' from becoming catastrophic

By 2050, #AntimicrobialResistance is expected to claim 10 million lives a year globally, more than cancer and diabetes combined, with most of this burden falling on low- and middle-income countries

Pfizer suspends sale, use of some products in India over quality concerns

Stockists have been asked not to sell, distribute, or use the products until further notice from Pfizer

Cow urine unfit for humans, contains harmful bacteria, says research body

Cow urine, which has been touted as a miracle medicine for decades, has now found to be unsuitable for direct human consumption

Your phone may carry bacteria found in human, animal faecal matter: Study

The results showed that 50 per cent of smartphone screens carried bacteria P. aeruginosa, commonly found in cockroach faeces

Don't use antibiotics in Covid till bacterial infection suspected: Govt

Antibiotics should not be used in Covid cases unless there is clinical suspicion of bacterial infection, according to a revised guideline for the treatment of adult coronavirus patients issued by the Centre. The revised guidelines, issued on Sunday amid an uptick in coronavirus cases, stated that drugs such as Lopinavir-ritonavir, hydroxychloroquine, Ivermectin, Molnupiravir, Favipiravir, Azithromycin and Doxycycline should not be used for the treatment of adult COVID-19 patients in India. The AIIMS/ICMR-COVID-19 National Task Force met on January 5 to revise the clinical guidance protocol. It has also advised doctors not to use convalescent plasma therapy. "Antibiotics should not be used unless there is clinical suspicion of bacterial infection. Possibility of co-infection of COVID-19 with other endemic infections must be considered," the guidelines said. Additionally, in moderate or severe diseases at high risk of progression, Remdesivir may be considered for up to five days. It

Researchers show new ways of tracking spread of infectious diseases

In previous work, Luis M. Rocha's group at the Instituto Gulbenkian de Ciencia (IGC) found a way to simplify networks by extracting their backbones

Regulators halt eye products' production at Global Pharma Healthcare site

Firm under US FDA scanner for bacterial contamination of its eye drops

Covid infection reshapes immune status depending on gender: Study

Scientists have found that the baseline immune statuses in men previously infected with SARS-CoV-2 was altered in ways that changed the response to an exposure different from SARS-CoV-2. The team of researchers systematically analyzed immune responses of healthy people who had been given the flu vaccine. From that data, they then compared the responses between those who had never been infected by SARS-CoV-2, the virus that causes COVID-19, and those who experienced mild cases but recovered. The team led by John Tsang, an immunobiologist from Yale University, US, found that immune systems of men who had recovered from mild cases of COVID-19 responded more robustly to flu vaccines than women who had had mild cases or men and women who had never been infected. "This was a total surprise," said Tsang. "Women usually mount a stronger overall immune response to pathogens and vaccines, but are also more likely to suffer from autoimmune diseases," said Tsang. The long-term effects of ...

Five bacteria types claimed 680,000 lives in India in 2019: Lancet study

Five bacteria types -- E. coli, S. pneumoniae, K. pneumoniae, S. aureus and A. baumanii -- caused nearly 6.8 lakh deaths in India in 2019, according to a study published in The Lancet journal. The analysis found that common bacterial infections were the second-leading cause of death in 2019, and were linked to one in eight deaths globally. There were 7.7 million (77 lakh) deaths in 2019 associated with 33 common bacterial infections, with five bacteria alone connected to more than half of all deaths, the researchers said. The deadliest bacterial pathogens and types of infection varied by location and age, they said. In India, five bacteria -- E. coli, S. pneumoniae, K. pneumoniae, S. aureus and A. baumanii -- were found to be the deadliest, causing 6,78,846 (nearly 6.8 lakh) deaths in 2019 alone, the researchers found. E. Coli was the most deadly pathogen, claiming 1,57,082 (1.57 lakh) lives in India in 2019, according to the study. Globally, bacterial infections were second only

Lupin ties up with global agencies to support tuberculosis treatment

Drug firm Lupin on Friday said it has tied up with Unitaid, The Aurum Institute, the Clinton Health Access Initiative (CHAI), and other global procurement agencies to support tuberculosis prevention treatment initiative to be rolled out to 138 countries. As per the agreement, the Mumbai-based firm will introduce two new formulations, a fixed-dose combination of Rifapentine + Isoniazid and Rifapentine 300 mg standalone tablets, at an affordable price in various regions, including many low-and middle-income countries with a large burden of tuberculosis (TB). "We are committed to enhancing the global access to affordable and high-quality drugs and APIs for the treatment of tuberculosis... "Through this, we will further reinforce our long legacy to provide shorter, more patient-friendly treatment options to prevent TB," Lupin Managing Director Nilesh Gupta said in a statement. Lupin is a leading player in the cardiovascular, anti-diabetic, and respiratory segments.

Is asymptomatic monkeypox case as infectious? Here's what experts say

The Union health ministry issued the 'Guidelines on Management of Monkeypox Disease' and stated that human-to-human transmission occurs primarily through large respiratory droplets

More than 1.2 mn people died from drug-resistant infections in 2019: Study

Drug-resistant bacteria and other microbes are rising due to the misuse and overuse of antibiotics, say health officials.

Black fungus: 106,300 vials of Amphotericin-B allocated to states, UTs

Union Minister for Chemicals and Fertilisers DV Sadananda Gowda on Monday said that 1,06,300 vials of black fungus drugs Amphotericin B have been allocated to states, union territories and to the Central Institutions."Ensuring significant availability of Liposomal #Amphotericin B, additional 106300 vials of the drug have been allocated across all the States/UTs and Central Institutions today," Sadananda Gowda said in a tweet.The Minister said that a total of 53,000 vials of Conventional Amphotericin B have also been allocated to all the states, UTs and Central Institutions today."A total of 53,000 vials of Conventional #Amphotericin B have also been allocated to all the States/UTs & Central Institutions today. The allocation of #ConventionalAmphotericin B is being made to ensure its smooth supply and timely treatment of patients," he said in another tweet.He further said that additional 9,400 vials of Liposomal Amphotericin B and 4,680 vials of Conventional Amphotericin B have ..

56% of Covid-19 patients with secondary infection die: ICMR study

Many patients needed potent antibiotics as they had superbugs and couldn't be treated with regular ones.

Decoded: Why are black, white and yellow fungal infections on the rise now?

What are these infections, why are their cases rising and how does one protect against them?