Page 111 - Health Medical Pharma
USFDA asks Alkem Labs to withhold manufacturing of a product at St Louis facility
Drug firm Alkem Laboratories Friday said it has received a letter from the US health regulator asking not to manufacture a particular product at its St Louis facility till a final decision is taken. The United States Food and Drug Administration (USFDA) had issued eight observations after inspecting the company's manufacturing plant at St Louis from January 14 to February 5 this year, Alkem Labs said in a filing to BSE. The company had submitted a detailed response to the eight observations that it had received during the pre-approval inspection for the product, it added. The company however did not provide any details about the product. "The company has now received a letter from USFDA informing that the manufacturing of the said product be withheld until the completion of the final evaluation by the USFDA and the final decision of USFDA shall be communicated to the company accordingly," the drug firm said. The said product is not being manufactured as it is awaiting approval from ...
Zydus Cadila receives final approval for Lurasidone Hydrochloride Tablets
The medication is used to treat certain mental/mood disorders such as schizophrenia, depression associated with bipolar disorder. It may also help to decrease hallucinations (hearing/seeing things that are not there).
USFDA inspects Cadila Healthcare's Pharmaceutical Technology Centre at Ahmedabad
At the end of the inspection, no observations (483) have been issued.
Emilia Clarke suffered life threatening aneurysms
Actress Emilia Clarke said she suffered two "life-threatening" aneurysms.
Alkem Laboratories update on USFDA inspection of its facility in St. Louis, USA
The Company has now received a letter from the USFDA informing that the manufacturing of the said product be withheld until the completion of the final evaluation by the USFDA and the final decision of the USFDA shall be communicated to the Company accordingly. It is to be noted that the said product is not being manufactured at this time as it is awaiting approval from US FDA.
Jubilant Life drops after USFDA inspection
Jubilant Life Sciences lost 3.1% to Rs 751.20 at 15:12 IST on BSE after the USFDA informed that the inspection at API manufacturing facility in Mysore has been classified as Official Action Indicated.
Compounds in coffee, cocoa may cut heart disease risk
Scientists have identified compounds found in coffee, cocoa and wine, that may reduce the risk of cardiovascular diseases, a study has found. The research by Kjeld Hermansen of Aarhus University Hospital in Denmark suggests that there is an association between the consumption of polyphenols and a reduction in cardiovascular diseases prevalence. Coffee is one of the main sources of polyphenols in the diet. The compounds naturally occur in the beverage and contribute to its unique flavours and aromas. In recent years there has been growing academic interest in the role of polyphenols in health through their antioxidant and anti-inflammatory effects. The research found that polyphenols may have a range of cardio protective functions but the precise mechanisms are not yet fully understood. It is suggested that they may alter cholesterol absorption and the processing of fats in the body, and reduce inflammation.
Zydus Cadila gets USFDA nod for generic mental disorders drug
Pharmaceutical firm Zydus Cadila Friday said it has received final approval from US health regulator to market lurasidone hydrochloride tablets used to treat mental disorders. The approval by the US Food and Drug Administration (USFDA) for lurasidone hydrochloride tablets is for multiple strengths of 20 mg, 40 mg, 60 mg, 80 mg and 120 mg. It will be manufactured at the group's manufacturing facility at SEZ, Ahmedabad, Cadila Healthcare, the listed entity of Zydus Cadila group, said in a regulatory filing. The medication is used to treat certain mental/mood disorders such as schizophrenia, depression associated with bipolar disorder, it added. The drug may also help to decrease hallucinations. Zydus Cadila group now has 257 approvals and has so far filed over 350 ANDAs since the commencement of the filing process in FY 2003-04, the filing said.
UK varsity students to give dental health help to India's poor
A team of 10 students from a British university will visit India to provide medical and dental aid to the underprivileged people with limited access to basic healthcare facilities. Led by Upen Patel and Ketan Patel, the dental students from the University of Birmingham, volunteering with the charity Satya Samaj UK, will arrive in Rishikesh for a four-day trip on Saturday. They will provide medical and dental aid to the poor people of Rishikesh and the surrounding areas in the Himalayan region. "The team will arrive in Rishikesh tomorrow and the volunteer activity camp takes places 9 am to 5 pm each day from Monday 25th to Friday 29th March," International Communications Manager, University of Birmingham Tony Moran told PTI. The group plans to work with local doctors and dentists to look after more than 500 adults and children at a special five-day dental, diabetes and asthma health camp, the university said in a statement on Thursday. "Maintaining good oral care is essential for ...
Childhood anxiety may up alcohol use disorders later
Children and teenagers who suffer from anxiety may be at an increased risk of developing alcohol use disorders in later life, a study has found. According to the research published in the journal Addiction, about 43 per cent of associations were positive, meaning that anxiety was associated with a higher likelihood of later alcohol use disorders. However, 11 per cent of associations were negative, with anxiety being associated with a lower likelihood of later alcohol use disorders. Approximately 30 per cent of associations were equivocal and 15 per cent were unclassifiable based on the information reported. Researchers noted that it is important to establish which anxious individuals consume more alcohol and develop alcohol use disorders in order to develop targeted interventions. "The evidence from prospective cohort studies is suggestive but not conclusive of a positive association between anxiety during childhood and adolescence and subsequent alcohol use disorder," said lead ...
Merck Foundation meets the President and the First Lady of Burundi
Merck Foundation, the philanthropic arm of Merck KGaA Germany underscored their commitment to building health care capacity in Burundi during their high-level meeting with the President of Burundi, Pierre Nkurunziza and the First Lady of Burundi, Denise Nkurunziza.The discussion was led by Prof Dr Frank Stangenberg Haverkamp, Chairman of the Executive Board of E Merck KG and the Chairman of Merck Foundation Board of Trustees and Dr Rasha Kelej, CEO of Merck Foundation to explain their health capacity building programs which were launched in partnership with the First Lady of Burundi together with Ministry of Health and Ministry of Communication and media, Merck Foundation said in a press release."Burundi welcomes the programs of Merck Foundation. These programs are going to be very critical and beneficial for our people and their social and economic well-being. I wholeheartedly support Merck Foundation in our country, to enable the success of all their programs with the aim to build ..
Females birds live longer when they have help raising offspring
Female birds age more slowly and live longer when they have help raising their offspring, according to a research. Studying the relationship between ageing and offspring rearing patterns in the Seychelles warbler, researchers at UK's University of Sheffield found that females who had assistance from other female helpers benefitted from a longer, healthier lifespan. The findings help explain why social species, such as humans, which live in groups and cooperate to raise offspring, often have longer lifespans. "It is well understood that one of the benefits of having relatives' help to raise offspring is that this improves the survival of the young," said professor Terry Burke, from the University of Sheffield's Department of Animal and Plant Sciences. "We have now shown that as parents age they decline in their ability to care for their offspring, but having helpers compensates for this effect, allowing the parents to continue to reproduce successfully into old age," Burke said. The ...
Here's a common link between Sleep and aging
As part of a recent study, researchers have found oxidative stress as the common link between sleep and aging.The research suggests that oxidative stress leads to sleep and is also believed to be a reason why we age. It is also seen as a cause of degenerative diseases."It's no accident that oxygen tanks carry explosion hazard labels: uncontrolled combustion is dangerous. Animals, including humans, face a similar risk when they use the oxygen they breathe to convert food into energy: imperfectly contained combustion leads to "oxidative stress" in the cell. This is believed to be a cause of aging and a culprit for the degenerative diseases that blight our later years. Our new research shows that oxidative stress also activates the neurons that control whether we go to sleep," explained Gero Miesenbock, lead researcher of the study.The team studied the regulation of sleep in fruit flies - the animal that also provided the first insight into the circadian clock nearly 50 years ago. Each ..
Study finds a promising combination for common paediatric brain tumour
A new study has found a new combination treatment for children suffering from brain tumour. The treatment aimed at resistant and recurrent low-grade gliomas slowed tumour growth and killed tumour cells in laboratory and mouse models.Paediatric low-grade glioma is the most common brain tumour in children and can often be treated with surgery alone. However, some patients have tumours in locations that make surgery too risky, such as near optic nerves or in the mid-brain area, or have their tumours grown back after surgery. The findings of the research were published in Neuro-Oncology Journal.Researchers at the Johns Hopkins Kimmel Cancer Centre and the Johns Hopkins University School of Medicine combined carboplatin, a standard chemotherapy drug that works well against these brain tumours, and everolimus, which blocks an enzyme called mTOR that was shown in earlier research to fuel the growth of these tumours. The combination increased DNA damage and cell death in laboratory ...
Emilia Clarke reveals she went through 2 life-threatening brain surgeries
In a shocking revelation on Thursday, 'Game of Thrones' actor 'Emilia Clarke' opened up about suffering from two brain aneurysms that nearly took her life.She revealed that the surgeries were difficult and so was her recovery. She also mentioned that these health issues started in 2011, soon after wrapping filming on the HBO show's first season, and that she was with her trainer when she felt a severe headache."My trainer had me get into the plank position, and I immediately felt as though an elastic band was squeezing my brain. I tried to ignore the pain and push through it, but I just couldn't. I told my trainer I had to take a break. Somehow, almost crawling, I made it to the locker room. I reached the toilet, sank to my knees, and proceeded to be violently, voluminously ill. Meanwhile, the pain -- shooting, stabbing, constricting pain -- was getting worse. At some level, I knew what was happening: my brain was damaged."Recalling the incident, Clarke said that she remembers a woman
Excess hormones may cause condition leading to blindness in women: study
Increased levels of hormones including testosterone could cause a brain condition that may lead to blindness in women, according to a research. Scientists at the University of Birmingham carried out the research which explores the role of hormones known as androgens in the way Idiopathic Intracranial Hypertension (IIH) develops. The IIH is caused by high pressure in the brain with consequences from blindness to incapacitating daily long-term headaches. IIH was originally identified over 100 years ago yet the cause of the condition has remained unknown, although there has been much speculation about why more than 95 per cent of total incidence is in women with obesity. "For over 100 years the cause of IIH has been unknown. These findings mark a key step forward; for the first time we have found a pattern of androgen dysregulation that is unique to IIH and potentially a driver of abnormal brain pressure in people with the condition," said corresponding and senior author of the study ...
Tea Board working on shrinking govt support: Bezbaruah
Tea Board of India was working on a shrinking government support with total allocation being approximately Rs 250 crore, an official said. "Tea Board is working under the backdrop of shrinking government financial support. The Board also labours under the burden of high administrative costs, with more than Rs 70 crore per year being spent on employees and maintenance of infrastructure, out of a total allocation of approximately Rs 250 crore", non-executive chairman of the board P K Bezbaruah told PTI. Thus, he suggested, one of the focus area of the Board over the next few years would be to reduce administrative costs by upto Rs 10 crore per annum, while many cost cutting initiatives were already on the anvil. "In my opinion, the thrust areas of the Board relating to the tea industry should be on exports through incentivization of exportable variants of tea, like orthodox, organic and speciality teas." The Board should attempt to get the incentive for production of such
Sports can have anti-depressant effects in preteen children
As part of a new study, researchers have linked participation in team sports to less depression in boys aged 9 to 11.Adult depression has long been associated with shrinkage of the hippocampus, a brain region that plays an important role in memory and response to stress. Now, the new research has linked participation in team sports to larger hippocampal volumes in children and less depression in boys ages 9 to 11."Our findings are important because they help illuminate the relationships between involvement in sports, a volume of a particular brain region and depressive symptoms in kids as young as nine," said Lisa Gorham, lead author of the study published in the Journal of Biological Psychiatry: Cognitive Neuroscience and Neuroimaging."We found that involvement in sports, but not non-sport activities such as music or art, is related to greater hippocampal volume in both boys and girls, and is related to reduced depression in boys," Gorham asserted.These relationships were ...
Eating breakfast with parents linked with positive body image for teenagers: Study
A family that eats together, stays together, and now, according to a recent study, consistently eating breakfast as a family can also promote positive body image for children and adolescents.The study suggests that parents hoping to raise teenagers with positive body image might just find helpful tools in the kitchen every morning."We know that developing healthy behaviours in adolescence such as eating breakfast every day and eating family meals can have long-term effects into adulthood. Children and adolescents are under a lot of pressure from social media and pop culture when it comes to physical appearance. Having a healthy relationship with food from eating breakfast and spending meal time with family might have a significant impact on well-being," said Virginia Ramseyer, one of the lead researchers.Researchers analyzed data from more than 12,000 students in more than 300 schools in all 50 states and Washington D.C. They looked at data related to eating behaviours, including ...
Lupin launches Levothyroxine Sodium Tablets USP
Lupin's Levothyroxine Sodium Tablets USP, is the generic equivalent of AbbVie, Inc's Synthroid Tablets. It is indicated for: