Page 133 - Health Medical Pharma

Lupin launches chronic angina treatment drug in the US

Drug maker Lupin Thursday announced exclusive launch of Ranolazine extended-release (ER) tablets, indicated for the treatment of chronic angina, in the US market. The newly launched product, in strengths of 500 mg and 1,000 mg, is a generic version of Gilead Sciences' Ranexa ER tablets, Lupin said in BSE filing. Quoting IQVIA MAT December 2018 data, Lupin said Ranolazine ER tablets, 500 mg and 1,000 mg had an annual sales of approximately USD 945 million in the US. "This is a meaningful product and further strengthens our portfolio of generic products in the US. Launching exclusive and semi-exclusive generics is an important stepping stone as we transition to more complex generics," Lupin Managing Director Nilesh Gupta said. "Products like Ranolazine bring significant savings to US consumers and are a key part of our vision to bring exclusive high quality, affordable medicines to the market, he added. Shares of Lupin were trading 0.29 per cent up at Rs 769.95 apiece on BSE.

Worldwide estimates suggest nearly 1 in 2 children with cancer are left undiagnosed, untreated

A new study, published in The Lancet Oncology journal estimates there are almost 4 lakh new cases of cancer annually, while current records only count around 2,00,000.The new study model makes predictions for 200 countries and estimates that undiagnosed cases could account for more than half of the total in Africa, South Central Asia and the Pacific Islands.Speaking about the study, lead author Zachary Ward said, "Our model suggests that nearly one in two children with cancer are never diagnosed and may die untreated."Ward further added, "Accurate estimates of childhood cancer incidence are critical for policy makers to help them set healthcare priorities and to plan for effective diagnosis and treatment of all children with cancer. While under-diagnosis has been acknowledged as a problem, this model provides specific estimates that have been lacking."The new model developed for this study, the Global Childhood Cancer microsimulation model, incorporates data from cancer registries in .

Coca-Cola India appoints new HR head for India, South West Asia

Beverage major Coca-Cola India Thursday announced appointment of Nishi Kulshreshtha Chaturvedi as Vice President, Human Resources, India and South West Asia. Chaturvedi will lead talent recruitment and advancement, performance enablement, and leadership development functions for the company in India and South West Asia, the company said in a statement. Coca-Cola said Chaturvedi, who joined the company in 2012 as National Head - Human Resources as part of Hindustan Coca-Cola Beverages Pvt. Ltd (HCCB), has risen through the ranks within the Coca-Cola system. "We at Coca-Cola are committed to developing and nurturing internal talent. Nishi has extensive experience and a natural flair for working with people in bringing out the best in them. We are looking forward to her leadership in developing resilient leaders for the company who can withstand the rapidly-evolving external environment and serve as role models for the next generation," Coca-Cola India and South West Asia President T ...

'Need detailed surveillance of Western Ghats to rein in mystery disease'

Scientists investigating the rise in cases of the mysterious Kyasanur forest disease (KFD) or 'monkey disease', which has killed over 300 people in recent years, mostly across the Western Ghats in Goa, Maharashtra and Karnataka, have sought detailed surveillance of the forested region and a holistic approach to tackle the viral haemorrhagic fever.

Lupin launches generic Ranolazine ER Tablets in U.S.

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Newly identified drug targets could open door for oesophageal cancer therapeutics

A new research has found that blocking two molecular pathways that send signals inside cancer cells could stave off oesophageal adenocarcinoma (EAC), the most common oesophageal malignancy in the United States.The study was conducted at the Case Western Reserve University School of Medicine. Researchers identified the pathways using advanced computational and genetic analyses of tumour biopsies from EAC patients. They found 80 percent of tumours had unusually active genes related to two specific pathways, and that exposing the cells to pathway inhibitors stymied EAC tumour growth in mice.The results of the study, published in Gastroenterology point to two signaling pathways (controlled by JNK and TGF-beta proteins, respectively) as contributing to EAC tumours.The pathways represent molecular chain reactions that were overactive in patient tumour cells, but not in biopsies from patients with non-cancerous oesophageal conditions, including Barrett's Oesophagus.Harmful effects of these ..

D-Alive Launches India's First Ever Range of Sauces and Salad Dressings for People With Diabetes

/ -- D-Alive Health Pvt. Ltd., India's first holistic wellness solutions provider for diabetes, has announced another industry first move. The company has introduced breakthrough sauces and salad dressings specially designed for people with diabetes, making it the country's maiden offering. D-Alive's sauces and vinaigrettes are made with 100% natural ingredients, completely free from all sort of adulterations, which otherwise is a constant worry when such condiments are consumed on a day-to-day basis. They are a nutritious mix of jamun and/or coconut vinegar (with mother) followed by various spices, seeds and herbs known for many medicinal values and anti-diabetic properties. Most variants available in the market are labels loaded with sugars, gluten and ingredient names one cannot even read, leaving them absolutely unaware of what is going in their body. On the other hand, D-Alive makes sure that even the oils used are cold-pressed, keeping nutrients intact which are otherwise ...

First semi-identical twins identified in pregnancy

Twins from Brisbane, a boy and a girl, have been identified as only the second set of semi-identical, or sesquizygotic, twins in the world. They are the first to be identified by doctors during pregnancy.The now four-year-old boy and girl are identical (monozygotic) on their mother's side sharing 100 per cent of their mother's DNA, but are like siblings on their father's side, sharing only a proportion of their father's DNA.This is the first case where semi-identical twins were identified on genetic testing while in the womb. It has been reported in The New England Journal of Medicine (NEJM) by Professor Nicholas Fisk and Dr Michael Gabbett.Notably, sesquizygotic represents a third type of 'twinning' between identical and fraternal (dizygotic)."It is likely the mother's egg was fertilised simultaneously by two of the father's sperm before dividing," said Professor Fisk, who led the foetal medicine team that cared for the mother and twins while based at Royal Brisbane and Women's ...

Colon cancer growth reduced by exercise: Study

A new study conducted by The University of Queensland in conjunction with the University of Waterloo, Ontario, has found that after a short session of high intensity interval training (HIIT), growth of colon cancer cells was reduced, and this also increased indicators of inflammation.The fact that exercise may play a role in reducing the growth of colon cancer cells has been published in The Journal of Physiology.For a long time, the focus on exercise has been on the positive changes in the body that occur following a longer period of training. However, these findings suggest that the effects following a single session of HIIT, an exercise regime involving short, high energy bursts are also important.According to the study, the changes following HIIT suggest that repeated exposure to the acute effects of exercise may contribute to the fight against the cancer. These results reinforce the importance of doing regular exercise and maintaining a physically active lifestyle.The study ...

Infosys arm to build hospitals in Karnataka

The global software major's philanthropic arm Infosys Foundation on Wednesday said it would build two hospitals in Karnataka, one each in Bengaluru and Ramanagara district.

Govt brings 42 non-scheduled cancer drugs under price control

The government has decided to bring 42 non-scheduled anti-cancer drugs under price control, capping trade margin at 30 per cent, an official statement Wednesday said. The National Pharmaceutical Pricing Authority (NPPA) has invoked extraordinary powers in public interest, under Para 19 of the Drugs (Prices Control) Order, 2013 to bring 42 non-scheduled anti-cancer drugs under price control through trade margin rationalisation, the statement said. "Invoking paragraph 19 of DPCO, 2013, the government hereby puts a cap on trade margin of 30 per cent and directs manufacturers to fix their retail price based on price at first point of sale of product... of the non-scheduled formulations containing any of the 42 drugs," the Department of Pharmaceuticals (DOP) said in a notification. As per data available with NPPA, the MRP for 105 brands will be reduced up to 85 per cent entailing minimum saving of Rs 105 crore to consumers, it added. Currently, 57 anti-cancer drugs are under price control .

Merck Foundation meets the Head of State and the First Lady of Zambia to launch their programs in the country

Merck Foundation, the philanthropic arm of Merck Germany underscored their commitment to building healthcare capacity in Zambia during their high-level meeting with The Head of State of Zambia, Edgar Lungu and The First Lady of Zambia, Esther Lungu at the State House of Zambia."The government will support initiatives that are aimed at addressing infertility in the country. I am happy that Merck Foundation and the First Lady of Zambia have come on board to deal with infertility. Some women have been abused and divorced because in the African context it is believed that only females are infertile, though infertility affects men and women both. I am also happy that the Merck Foundation has trained journalists to understand infertility as the media is a front line in communication and that training them is the key to address challenges surrounding infertility", emphasized Edgar Lungu, the Head of State of Zambia. Merck Foundation launched its programs in Zambia in partnership with The ...

Infosys Foundation to help build 300-bed hospital complex

Infosys Foundation, the philanthropic and corporate social responsibility arm of Infosys, will help build a 300-bed hospital complex in the Jayadeva Institute of Cardiovascular Science and Research here. Chief Minister H D Kumaraswamy laid the foundation stone in the presence of Infosys Foundation chairperson Sudha Murthy, tourism minister S R Mahesh and the director of Jayadeva Hospital, Dr C N Manjunath. The project aims to help reduce the congestion faced by the hospital and also treat poor patients from various parts of the country, a Foundation release said. Infosys Foundation signed a Memorandum of Understanding with Jayadeva Hospital, it said. The Foundation has also agreed to help construct a 100-bed capacity maternal and child care hospital in Kanakapura in the adjoining Ramanagara district of Bengaluru, the release added.

National drug pricing regulator fixes retail value of 36 formulations

NPPA fixes ceiling and retail prices of essential medicines of Schedule I under the Drugs Order 2013

Tobacco plants can help treat diabetes, stroke

Tobacco plants can be used as 'green bioreactors' to produce a potentially powerful therapeutic that could treat a number of disorders like diabetes, stroke, dementia and arthritis, scientists say. The plants are being used to produce large quantities of a human protein called Interleukin 37, or IL-37. The protein is naturally produced in the human kidney in very small quantities and has powerful anti-inflammatory and immune-suppressing properties, providing potential for treating a number of inflammatory and autoimmune disorders like type 2 diabetes, stroke, dementia and arthritis. "This protein is a master regulator of inflammation in the body, and has been shown in pre-clinical models to be effective in treating a whole host of diseases," said Tony Jevnikar, a professor at Western University in Canada. "The human kidney produces IL-37, but not nearly enough to get us out of an inflammation injury," said Jevnikar. While showing promise in animal models, IL-37's use clinically has ...

Steroid injections linked to lower infant birth weights: Study

Steroid injections given to mothers at risk of giving birth prematurely are likely to deliver babies with lower body weights, says a new study.

AI tool can screen for foetal alcohol spectrum disorder

Scientists have developed an artificial intelligence tool that cab screen children for foetal alcohol spectrum disorders quickly and affordably, making it accessible to more children in remote locations worldwide. Foetal alcohol spectrum disorders (FASDs) are a group of conditions that can occur in a person whose mother drank alcohol during pregnancy. Problems may include an abnormal appearance, short height, low body weight, small head size, poor coordination, low intelligence, behaviour problems, and problems with hearing or seeing. The tool uses a camera and computer vision to record patterns in children's eye movements as they watch multiple one-minute videos, or look towards or away from a target. It then identifies patterns that contrast to recorded eye movements by other children who watched the same videos or targets, according to the scientists from Queen's University in Toronto, University of Southern California and Duke University in the US. The eye movements outside the ...

Tobacco plant may aid in treating diabetes, arthritis

Tobacco plants can be used to produce an anti-inflammatory protein that can have powerful therapeutic potential for treating conditions like Type-2 diabetes, stroke, dementia and arthritis, more effectively and at an affordable price, researchers say.

ML tool to identify kids with alcohol-related developmental disorder

Researchers have developed a new tool that uses Machine Learning (ML) technology to screen children suffering from a type of developmental and neurobehavioural disorder, caused due to alcohol exposure while in the womb, quickly and at an affordable rate.

Docprime.com achieves 1 million unique visitors mark

Docprime.com, the latest healthcare venture by EtechAces Marketing and Consulting Private Limited ("Policybazaar Group") has achieved its first milestone of one million unique visitors per month. The milestone has been accomplished in a short span of 6 months after the launch of Docprime services.The platform which offers free online medical consultations, preventive healthcare packages and cashless services for a doctor and diagnostic lab appointments has quickly become a preferred choice across age groups. Millennials and digital natives between the age group of 18-25 and 25-30 form the highest segment of unique visitors at 52%, proving that the platform is tapping into an unmet need for the population. A further 17% of the users are split between the age group of 30-40. Surprisingly, even the traditionally non-savvy internet users in the age group of 40 and above are also now preferring to consult a doctor online.An analysis of the visitor traffic threw up some interesting results.