JERUSALEM (Reuters) - Israeli biopharma firm BiomX said on Wednesday it raised $32 million in a private funding round that will primarily be used to advance the company's drug candidates for the treatment of acne and inflammatory bowel disease (IBD).
Intake of widely prescribed drugs to neutralise stomach acid by people with heartburn or stomach ulcers could be associated with increased risk of kidney disease, warns a study of over 40,000 patients.
Human papillomavirus (HPV) screening and vaccination must be taken up on a war footing in countries like India to prevent 15 million cervical cancer deaths among women by 2050, a Lancet research said.
A new study now finds scientists saying that variety in social circle may help a person live longer.Researchers at The University of Texas at Austin have found that older adults who spend more time interacting with a wide range of people were more likely to be physically active and had greater emotional well-being.In a paper out today in the Journals of Gerontology Series B: Psychological Sciences and Social Sciences, researchers found that study participants who interacted more with family members and close friends, as well as acquaintances, casual friends, service providers and strangers were more likely to have higher levels of physical activity, less time spent sitting or lying around, greater positive moods and fewer negative feelings. It is the first study to link social engagement with physical activity throughout the day.Speaking about it, study author Karen Fingerman said, "Adults often grow less physically active and more sedentary as they age, and these behaviours pose a ...
Researchers have now developed a new way to deliver treatment for cartilage regeneration.The study, conducted at Texas A&M University was led by Dr. Akhilesh K. Gaharwar.Gagarwar said the nanoclay-based platform for sustained and prolonged delivery of protein therapeutics has the potential to impact treating osteoarthritis, a degenerative disease that affects nearly 27 million Americans and is caused by breakdown of cartilage that can lead to damage of the underlying bone.According to study experts, one of the greatest challenges with treating osteoarthritis and subsequent joint damage is repairing the damaged tissue, especially as cartilage tissue is difficult to regenerate.One method for repair or regeneration of damaged cartilage tissue is to deliver therapeutic growth factors. Growth factors are a special class of proteins that can aid in tissue repair and regeneration. However, current versions of growth factors break down quickly and require a high dose to achieve a ...
Sonu Nigam who was admitted to Norvic International Hospital after complaining of acute back pain has been discharged from the hospital Wednesday afternoon.The singer, who was in the Himalayan Nation for a musical concert at Pokhara, was admitted to the hospital in Kathmandu, following acute back pain. RP Manali, Deputy General Manager of Corporate Communication from the hospital had confirmed the news saying that an MRI was done and they were awaiting reports for further treatment.With the treatment done, Nigam has been discharged and is said to be leaving for India on Wednesday itself, the hospital informed ANI.The Indian singer was attended by Dr. Prabin Nepal and Dr. Pankaj Jalan.Nigam was scheduled to leave for India on Tuesday itself but had to be rushed to the hospital following health complaint.
Haryana Governor Satyadeo Narain Arya on Wednesday reiterated the resolve of Chief Minister Manohar Lal Khattar led BJP government to "provide affordable, accessible, equitable and quality healthcare services to the people of the state."To ensure this, special emphasis is being given to improving the quality of health services in health institutions," said he, while addressing the Haryana Vidhan Sabha on the opening day of the Budget Session here.He said that the state government is committed to providing nutritional and health benefits to the poorest of the poor. "Haryana has become the first to implement the ambitious scheme of 'Ayushmaan Bharat,' which provides for medical benefits up to Rs 5 lakh to the poor families," he said."Over 5 lakh citizens have been registered under this scheme and 357 hospitals have been empanelled and claims of an amount of about Rs 7 crore has been paid till now," he further informed.He said that the Quality Assurance Programme is being implemented ...
With help from a dozen clinical variables, researchers have been able to identify, using machine learning techniques, which of their patients with severe asthma are likely to benefit from treatment with systemic corticosteroids -- and which might only suffer their side effects.The newly identified set of variables, when processed by computer software, will yield more precise predictions of a patient's response, said lead study authors Wei Wyu.Wu said, "Systemic corticosteroids are the most effective therapy we have for asthma, but not all patients respond in the same way," adding, "Unfortunately, when clinicians don't see a big improvement after initial treatment, they might give patients even higher doses. If a patient is one of those who can't be helped by corticosteroids, the higher dose just means worse side effects."The study, led by Wu and Dr. Sally E. Wenzel, was recently published online by the American Journal of Respiratory and Critical Care Medicine.Asthma causes wheezing, .
A new research now finds scientists from the University of Sheffield discover a compound that could be more effective in treating a few types of cancers than standard chemotherapy.While chemotherapy is still the first line of defence for most cancer tumours and is often highly effective, many cancers are naturally resistant, or develop resistance, to commonly used first-line chemotherapy drugs like cisplatin.Researchers identified new drug-candidates that would work against these types of treatment resistant cancers.The paper was published in the Journal of the American Chemical Society.In the study, scientists screened new compounds made in the lab against a "panel" of cancers that were sensitive and resistant to standard cancer therapy. They further tested the compounds with non-malignant cells to see how toxic they were to normal cells.They found two lead compounds that had low toxicity to non-malignant cells but were highly active against cancer cells sensitive or resistant to ...
Decks have been cleared for Dr Reddys Laboratories to launch the copycat version of Suboxone, a sublingual film, as the US Supreme Court has turned down UK pharma firm Indivior's plea to stay a lower courts order that paved the way for the launch. Indivior is in legal battle against the launch of copycat version of its opioid addiction treatment by competitors including Dr Reddy's Laboratories in the US market. "On February 19, the Supreme Court of the United States denied Indivior's motion to stay issuance of the US Court of Appeals for the Federal Circuit's (CAFC's) mandate vacating the Preliminary Injunction (PI) granted against DRL. The CAFC subsequently issued the mandate vacating the PI granted against DRL," Indivior said in a regulatory filing. Following the top Court order, Indivior PLC Wednesday announced that its US affiliate, has launched an authorized generic version of Suboxone (buprenorphine and naloxone) Sublingual Film in the US market. On Indivior's ...
Exercising can help counter the effects of jet lag, shift work, and other disruptions to the body's internal clock and help people cope with erratic schedules. The researchers from University of California, San Diego and Arizona State University in the US examined body clocks following exercise in 101 participants for up to five and a half days. The circadian "body"' clock is the 24 hour cycle that regulates many physiological processes including sleeping and eating. Many factors affect this internal body clock including light and time cues. Exercise has been known to cause shifts in the circadian clock however very little is known about this effect. The study, published in The Journal of Physiology, showed that exercising at 7 am or between 1 and 4 pm advanced the body clock to an earlier time, and exercising between 7 and10 pm delayed the body clock to a later time. Exercising between 1 and 4 am and at 10 am, however, had little effect on the body clock, and the phase-shifting ...
Eating a handful of tree nuts daily, such as almonds, walnuts and pistachios, may reduce the risk of cardiovascular disease among people with type 2 diabetes, researchers, including one of Indian origin, have found. According to the study published in the journal Circulation Research, type 2 diabetes is associated with an increased risk for high cholesterol, heart disease and stroke. Nuts are full of unsaturated fatty acids, phytochemicals, fibre, vitamin E and folate, as well as minerals including calcium, potassium and magnesium, said researchers from the Harvard TH Chan School of Public Health in the US. However, little is known about the health benefits, if any, that nuts might offer people with type 2 diabetes who face a greater risk for heart health complications, they said. Researchers used self-reported diet questionnaires from 16,217 men and women before and after they were diagnosed with type 2 diabetes and asked them about their consumption of both peanuts and tree nuts ...
Finding it hard to cope with jet lag, shift-based work? Doing some excercise can shift the human body clock and help you adjust to the shifted schedules, suggests new research.
Scientists have developed a gene editing therapy that can slow down ageing in mice with progeria syndrome, a rare genetic disorder that also afflicts humans. The research, published in the journal Nature Medicine, provides insights into the molecular pathways involved in accelerated ageing, as well as how to reduce toxic proteins via gene therapy. Ageing is a leading risk factor for a number of debilitating conditions, including heart disease, cancer and Alzheimer's disease. This makes the need for anti-ageing therapies all the more urgent. Scientists from the Salk Institute in the US highlight a novel CRISPR/Cas9 genome-editing therapy that can suppress the accelerated ageing observed in mice with Hutchinson-Gilford progeria syndrome, a rare genetic disorder that also afflicts humans. "Ageing is a complex process in which cells start to lose their functionality, so it is critical for us to find effective ways to study the molecular drivers of ageing," said Juan Carlos Izpisua ...
The product will be manufactured at flagship facility in Bangalore and will be marketed by Strides Pharma Inc. in the US market.
The apex consumer forum has directed three doctors to pay Rs 2.7 lakh for "gross-negligence" and "mismanagement" that led to the death of a woman after she suffered a cardiac arrest during an operation and slipped into a coma and never recovered from it. The National Consumer Disputes Redressal Commission (NCDRC) said that it was a "serious lapse" on the part of the doctors to not assess the woman's cardiac condition before the operation. A bench of presiding member Anup K Thakur and member C Vishwanath upheld the district consumer forum's order asking Doctors Zubedaben Desai, Kashyap Rameshbhai Shah and Rachnaben Jigneshbhai Shah of Ahmedabad, Gujarat, to pay Rs 2.7 lakh to Mustafabhai Ibrahimbhai Salar for the death of his wife, Memunaben Salar. According to the complaint, Salar was admitted to Ahmedabad's Samved hospital on October 20, 2004. She suffered a cardiac arrest during the surgery the next day. She was shifted to another hospital where she remained in coma till her death ..
Cervical cancer could be eliminated as a public health problem in India within the next 60 years by making existing prevention programmes such as the human papillomavirus (HPV) vaccine and cervical screening more accessible, according to a Lancet study published Wednesday. The estimates, which are the first of their kind at a global-scale, indicate that up to 13.4 million cases of cervical cancer could be prevented within 50 years if intervention strategies are scaled-up by 2020. The average rate of annual cases across all countries could fall to less than 4 cases per 100,000 women by the end of the century -- which is a potential threshold for considering cervical cancer to be eliminated as a major public health problem. For countries with medium levels of development, including India, Vietnam, and the Philippines, this could be achieved by 2070-79, according to the study published in The Lancet Oncology journal. The study, led by researchers at the Cancer Council New South Wales in .
Drug firm Alembic Pharmaceuticals Friday said it has received approval from the US health regulator for Acetazolamide extended-release capsules, used for treatment of various kinds of glaucoma. The approved product is therapeutically equivalent to the reference listed drug Diamox Sequels, 500 mg, of Teva Branded Pharmaceutical Products R&D Inc. The company has received approval from the US Food and Drug Administration (USFDA) for its abbreviated new drug application (ANDA) Acetazolamide extended-release capsules, 500 mg," Alembic Pharmaceuticals said in a BSE filing. Quoting IQVIA sales data, the company said, Acetazolamide extended-release capsules, 500 mg has an estimated market size of USD 13.1 million for 12 months ending December 2018. Acetazolamide extended-release capsules are also indicated for the prevention or amelioration of symptoms associated with acute mountain sickness despite gradual ascent. The company said it now has a total of 87 ANDA approvals from the ...
Strides Pharma Science Wednesday said its step-down wholly-owned subsidiary has received approval from the US health regulator for Ethosuximide Softgel capsules, an anti-epileptic medication. The approved product is a generic version of Zarontin Capsules, 250 mg, of Pfizer. "Strides Pharma Global, Singapore, has received approval for Ethosuximide Softgel Capsules USP, 250 mg, from the United States Food and Drug Administration (USFDA)," Strides Pharma Science said in a BSE filing. The product was approved in the first review cycle by the USFDA in less than 10 months of filing. Citing IQVIA data, the company said the US market for Ethosuximide Softgel Capsules USP, 250 mg, is approximately USD 10 million. Strides said Ethosuximide Softgel capsules are part of its niche and small volume product portfolio with limited competition in the US market. "As part of its portfolio maximisation strategy, Strides will also commercialise the product in other geographies, leveraging its vast ...
/ -- Essilor Vision Foundation is delighted to announce the support of the program 'Blindness Free Maharashtra' launched by the Government of Maharashtra in collaboration with the not-for-profit organization Ratna Nidhi Trust. Through this initiative, approximately 2.5 million children from underserved communities will be provided with free eye care and spectacles if needed. Over a period of three years, from 01 April 2019 to 31 March 2022, the Government of Maharashtra and Ratna Nidhi will organize several screening events for children in need. In line with its mission to eliminate poor vision and its lifelong consequence, Essilor Vision Foundation will support these initiatives by donating 150,000 pairs of spectacles to children who can't see clearly. The launch of the program is expected to be presided over by the Honorable Chief Minister of Maharashtra Mr. Devendra Fadnavis, IAS, Secretary, Medical Education and Drug Department (MEDD) Dr. Sanjay Mukherjee, along with Senior ...