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Painless method can evaluate tumour progression

IANS  |  Beijing 

Chinese researchers have developed a new evaluating model using to help painlessly evaluate progression in patients.

Doctors usually use the biological characteristics of to observe the progress and response to treatment, such as if there are gene mutations or malignant features. Previous studies have shown that identifying the biological characteristics may contribute to better treatment and may increase survival rates.

Traditional methods to get tissue include and puncture, which are invasive, painful and costly.

So the researchers built a computer model to make assessments based on tissue characteristics captured by a technique, reported.

The research, published in the journal European Radiology, focused on and involved 345 patients with rectal tumour cells who underwent multiparametric (MP-MRI), from June 2013 to October 2016.

Through MP-scanning, researchers extracted thousands of imaging features from 197 patients and selected five typical ones as biomarkers to show the characteristics of tumour cells, including how they grow and spread.

They built a model with these biomarkers and fed it images of the other 148 patients, who had surgeries to evaluate tumour progression two weeks later after MP-scanning.

"The evaluation results of the model are more than 60 per cent similar with that of traditional methods," said from the and Technology.

"Despite these positive results," Gao said, "more data is still needed to confirm the validity and reliability of the model."

The research team is also testing the model in patients with breast cancer, ovarian cancer, and

Apart from MRIs, more techniques such as and computed (CT) are being integrated with the latest technologies, to non-invasively and repeatedly capture tumour characteristics.

"The imaging techniques are painless, and their cost will be lower than that of or puncture," Gao noted.

"It can also provide complementary information in evaluating specific tumour types when doctors can't get the tumour tissue through traditional invasive methods."



(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Sun, December 02 2018. 10:44 IST