The Premier League fixture Saturday was Cardiff's first since the Argentinian striker's body was formally identified by an English coroner on Thursday, a day after it was recovered from underwater wreckage in the Channel.
Southampton confirmed both fans had been spoken to by police and intended to take "an extremely firm stance" over the incident.
"Such behaviour has no place in our game and will not be tolerated at St Mary's.
"The club will be taking an extremely firm stance against anyone involved and intends to ban those supporters identified," the statement added.
Before Saturday's kick-off there was an impeccably observed minute's silence at the ground with Cardiff going on to win 2-1 thanks to Kenneth Zohore's dramatic goal in the third minute of stoppage time which saw them climb out of the relegation zone.
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)