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Genetics may have a part to play in insomnia

ANI  |  Washington D.C. [U.S.A.] 

problems may be associated with specific genes in our bodies.

Research indicates that there is a genetic link between and such as depression, or physical conditions such as type 2

Survey shows that up to 20 percent of Americans and up to 50 percent of US military veterans are dealing with problems. can seriously affect a person's and make them weak internally.

Chronic can cause various long-term issues such as and type 2 diabetes, as well as mental illness, such as (PTSD) and suicide.

Twin studies show that various sleep-related characteristics, including insomnia, are heritable. With the help of these findings, researchers have now started looking into the specific gene variants involved. Such studies are crucial in figuring out the reason behind and other such problems.

"A better understanding of the molecular bases for will be critical for the development of new treatments," says of the and the VA San Diego

In this study, Stein's research team conducted genome-wide association studies (GWAS). DNA samples obtained from more than 33,000 soldiers taking part in the Army Study To Assess Risk and Resilience in Servicemembers (STARRS) were analyzed.

Data from soldiers of European, African and Latino descent were grouped separately to identify the influence of specific ancestral lineages. Stein and his colleagues also compared their results with those of two recent studies that used data from the

All in all, the study confirms that is partially hereditary.

"The genetic correlation between disorder and other psychiatric disorders, such as major depression, and such as type 2 suggests a shared genetic diathesis for these commonly co-occurring phenotypes," says Stein.

was linked to the occurrence of specific variants on chromosome 7. In people of European descent, there were also differences on chromosome 9. The variant on chromosome 7, for example, is close to AUTS2, a gene that has been linked to alcohol consumption, and others that relate to brain development and sleep-related electric signaling.

Stein further says, "Several of these variants rest comfortably among locations and pathways already known to be related to and circadian rhythms. Such associated loci may contribute to the genetic risk underlying a range of conditions including and "

The findings from the study are published in the journal, Molecular Psychiatry.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Sat, March 10 2018. 13:25 IST