By Saturday afternoon, Missouri troopers had responded to more than 3,000 calls for help, involving more than 700 crashes and 1,300 stranded vehicles.
In central Missouri, about 12,000 households and businesses suffered power failure at one point, media reported.
The snowstorm also hit Chicago, the third largest US city, which has put a winter weather advisory.
It is expected that the storm will bring three to six inches of snow to Washington D.C. and some areas in northern and central parts of Maryland on Sunday before reaching into the mid-Atlantic region.
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)