Page 155 - Health Medical Pharma
High-risk HPV may up heart disease risk: Study
Infection with high-risk strains of the human papillomavirus (HPV), which have been linked to cancer, might increase the risk of cardiovascular disease, a study warns. While cardiovascular disease has known risk factors -- such as cigarette smoking; high cholesterol, high blood pressure, physical inactivity, poor diet, obesity and diabetes -- to prevent cardiovascular disease, it is important to uncover other potential contributors. One potential contributor is the most common sexually transmitted disease worldwide -- the human papillomavirus or HPV, according to researchers from Kangbuk Samsung Hospital in South Korea. Certain strains of HPV are considered high risk because they can increase the risk of certain kinds of cancer, especially cervical, but also vaginal, vulvar, penile as well as mouth and throat. A pap test can detect abnormal cells in the cervix, but HPV infection often has no symptoms until cancerous cells develop. In the study published in the journal Circulation ...
High-risk HPV contribute to increased CVD risk: Study
While human papillomavirus (HPV) have been linked to cancer, infection with high-risk strains of the virus might also increase the fear of cardiovascular disease (CVD), especially among women with obesity or other cardiovascular problems, according to a new research.
Philippines hit by deadly measles outbreak
A growing measles outbreak in the Philippines killed at least 25 people last month, officials said Thursday, putting some of the blame on mistrust stoked by a scare over an anti-dengue fever vaccine. Most of the dead are children and the toll is expected to rise as more cases are confirmed of the highly contagious disease, which has made a worldwide resurgence in recent years. Figures from the Philippines' national health authorities show cases jumped from 791 in 2017 to 5,120 last year. There were 1,813 confirmed cases in January alone. The most recent numbers available show measles killed 30 in the first eight months of last year, and five in all of 2017. Authorities said vaccination rates in the Philippines have been declining for years, but also pointed to the recent controversy over the safety of the Dengvaxia dengue vaccine. "The measles vaccination coverage has been in decline in the last five years," health undersecretary Eric Domingo told a press conference Thursday. "In the .
No confirmed KFD case in DK district: Health dept
No confirmed case of Kyasanur Forest Disease (KFD), also known as monkey fever, has been reported from any part of Dakshina Kannada district,a health official said. The tests on samples of dead monkeys and blood samples of suspected patients from the district at the National Institute of Virology, Pune have been negative for KFD, districthealth officer M Ramakrishna Rao told reporters here Wednesday. Five suspected cases had been reported so far in the district. Rao said 22 monkeys were found dead in various parts since the KFD broke out in neighbouring districts. Autopsy conducted on the dead monkeys also did not confirm that theydied of the disease. The health department is keeping a close watch on the situation and continuing the tests and people in the district need not panic, he said.
Tests on human blood plasma products negative for HIV: Chinese health officials
Chinese health officials on Thursday said tests conducted on a batch of human blood plasma, which was feared to have been contaminated with HIV, came out to be negative for the AIDS causing virus. The officials were probing reports that a Chinese pharmaceutical company may have sold over 12,000 units of a blood plasma product contaminated with HIV. The results of nucleic acid test (NAT) for HIV, hepatitis B and hepatitis C on the drugs manufactured by Shanghai-based China Meheco Xinxing Pharma Co Ltd were all negative, the National Medical Products Administration (NMPA) said in a statement. The HIV tests conducted on patients in Jiangxi were also negative, state-run Xinhua news agency reported. The NMPA said the samples they had examined from a batch of 12,229 bottles of intravenous immunoglobulin were free of HIV and hepatitis B and C. The administration's clearance of the batch contradicted a notice from the National Health Commission on Tuesday announcing its contamination and ...
Glenmark gets tentative USFDA nod for generic advanced breast cancer injection
Drug firm Glenmark Pharmaceuticals Thursday said it has received tentative approval from the US health regulator for generic Fulvestrant injection used for treatment of advanced breast cancer in postmenopausal women. Glenmark Pharmaceuticals Inc, USA, has been granted tentative approval by the United States Food & Drug Administration (USFDA) for Fulvestrant injection, 250 mg/5 mL (50 mg/mL), the company said. The product is a generic version of AstraZeneca Pharmaceuticals LP's Faslodex injection in the same strength, it added. The Faslodex injection 250 mg/5 mL (50 mg/mL) brand and all available therapeutic equivalents achieved annual sales of around USD 533.3 million, Glenmark said. The company's current portfolio consists of 148 products authorised for distribution in the US market and 54 abbreviated new drug applications (ANDA's) pending approval with the USFDA. The injection is used for treatment of hormone receptor positive, human epidermal growth factor receptor 2 - negative
Lupin gets USFDA nod for generic version of Tadalafil tablets
Drug firm Lupin Thursday said it has received approval from the US health regulator to market a generic version of Tadalafil tablets, used to treat pulmonary arterial hypertension. The company has received approval from the US Food and Drug Administration (USFDA) to market a generic version of Eli Lilly and Company's Adcirca tablets in 20 mg strength, Lupin said in a statement. It is indicated for the treatment of pulmonary arterial hypertension (PAH) to improve exercise ability. As per IQVIA MAT December 2018 data, Lupin said, the Tadalafil tablets, 20 mg had annual sales of around USD 474.3 million in the US. Lupin shares were trading 2.42 per cent down at Rs 821.85 apiece on the BSE.
Cipla gets USFDA nod for generic pulmonary arterial hypertension drug
Drug major Cipla Thursday said it has received nod from the US health regulator for its generic Tadalafil tablets used for treatment of pulmonary arterial hypertension. The company has received final approval for its abbreviated new drug application (ANDA) for Tadalafil tablets in the strength of 20 mg from the United States Food and Drug Administration (USFDA), Cipla said in a statement. The product is a generic version of Eli Lilly & Co's Adcirca tablets, it added. According to IQVIA (IMS Health), Adcirca and its generic equivalents had US sales of about USD 490 million for the 12-month period ended November 2018, the statement said. The company's product is available for shipping immediately, it added. The Tadalafil tablets are indicated for the treatment of pulmonary arterial hypertension to improve exercise ability, it said. Shares of Cipla were trading at Rs 533.90 per scrip on the BSE, up 1.13 per cent from the previous close.
China says tests on plasma products negative for HIV
Chinese investigators said Thursday tests on a batch of a plasma product feared to have been contaminated with HIV have turned up negative for the virus that causes AIDS. The result appears to have headed off the possibility of yet another scandal involving medical products in the country. Incidents include the falsifying of production records for rabies vaccines that prompted a nationwide crackdown on the industry and the injecting of other faulty vaccines. Public outrage over such scandals has alarmed the leadership of the ruling Communist Party, moving it to respond more quickly and firmly than in the past, including bringing criminal charges and billion dollar fines. A statement from the National Medical Products Administration said tests for HIV, hepatitis B and hepatitis C all turned out negative. The samples were from a batch of 12,000 plasma products manufactured by Shanghai-based China Meheco Xinxing Pharma Co., Ltd. The National Health Commission on Tuesday reported to the ..
Vitamin D may help treat lethal drug-resistant TB
Taking vitamin D supplements with antibiotics can help speed up the process of clearing multi-drug resistant tuberculosis bacteria from the lungs, a study claims. The World Health Organisation estimates that 10.0 million people developed active tuberculosis (TB) in 2017, and that 1.6 million people died of this disease. "Multi-drug resistant TB is on the rise globally. It's notoriously difficult to treat, and it carries a much worse prognosis than standard TB," said Adrian Martineau from Queen Mary University of London in the UK. Multi-drug resistant (MDR) TB is caused by bacteria that are resistant to treatment with at least two of the most powerful first-line anti-TB drugs, causing around 500,000 cases and 150,000 deaths per year worldwide. Existing antibiotic treatments for MDR TB are lengthy, costly and often toxic due to their serious side effects. "Our study raises the possibility that vitamin D -- which is very safe and inexpensive -- could benefit this hard-to-treat group of ..
Vitamin D helps combat drug-resistant TB: Study
Vitamin D, commonly known as the "sunshine vitamin", can combat tuberculosis (TB) bacteria found in the lungs of people with multi-drug resistant TB, according to latest research.
How our brain resolves moral vs material conflict
People have a moral preference for supporting good causes and not wanting to support harmful or bad causes, according to a study which analysed how our brain resolves conflicts between moral and material motives. Researchers at the University of Zurich in Switzerland noted that when donating money to a charity or doing volunteer work, we put someone else's needs before our own and forgo our own material interests in favour of moral values. Studies have described this behaviour as reflecting either a personal predisposition for altruism, an instrument for personal reputation management, or a mental trade-off of the pros and cons associated with different actions. The study, published in the journal eLife, investigated the neurobiological origins of unselfish behaviour. The researchers focused on the right Temporal Parietal Junction (rTPJ), an area of the brain that is believed to play a crucial role in social decision-making processes. To understand the exact function of the rTPJ, ...
Batch of 12,000 blood plasma found contaminated with HIV in China
A batch of over 12,000 human blood plasma has been found contaminated with HIV in China and the government has launched a probe into the latest medical scandal in the country.
How binge drinking causes lasting brain changes in teens
Heavy drinking in adolescence has lasting effects on the brain wiring, and may increase the risk of psychological problems and alcohol use disorder later in life, say scientists, including one of Indian origin. Researchers at the University of Illinois in the US have shown that some of these lasting changes are the result of epigenetic changes that alter the expression of a protein crucial for the formation and maintenance of neural connections in the amygdala -- the part of the brain involved in emotion, fear and anxiety. Their results, published in the journal Translational Psychiatry, are based on the analysis of postmortem human brain tissue. Epigenetics refers to chemical changes to DNA, RNA or specific proteins associated with chromosomes that change the activity of genes without changing the genes themselves. Epigenetic modifications are involved in the normal development of the brain, but they can be influenced by environmental or even social factors, such as alcohol and ...
Lupin receives USFDA approval for Tadalafil Tablets
Tadalafil Tablets, 20 mg (RLD: Adcirca) had annual sales of pproximately USD 1174.3 million in the US (IQVIA MAT December 2018).
AstraZeneca Pharma sizzles after turnaround Q3 result
AstraZeneca Pharma India jumped 10.37% to Rs 1,772.70 at 09:25 IST on BSE after the company reported net profit of Rs 29.09 crore in Q3 December 2018 as against net loss of Rs 10.35 crore in Q3 December 2017.
Cipla receives USFDA final approval for Tadalafil Tablets 20mg
Cipla's Tadalafil Tablets 20mg is AB-rated generic therapeutic equivalent version of Eli Lilly & Co.'s Adcirca . It is a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) to improve exercise ability. According to IQVIA (IMS Health), Adcirca and its generic equivalents had US sales of approximately $490M for the 12-month period ending November 2018. The product is available for shipping immediately.
Glenmark Pharmaceuticals receives tentative ANDA approval for Fulvestrant Injection
According to IQVIATM sales data for the 12 month period ending December 2018, the FASLODEX Injection, 250 mg/5 mL (50 mg/mL) market2 achieved annual sales of approximately $533.3 million.
Health ministry scrambles to assist states in containing swine flu cases
In view of soaring cases of swine flu and deaths due to the disease in 11 states, including Rajasthan, Gujarat and Punjab, the Union Health Ministry has deputed a public health team to Rajasthan to assess the situation and assist the state in strengthening its response. Union Health Secretary Preeti Sudan also directed officials to send additional teams to Gujarat and Punjab. States have also been advised to involve district collectors in enhancing public awareness and outbreak response, a health ministry statement said. The death toll in the country this year due to swine flu has soared to 226 with the H1N1 virus claiming 31 more lives in a week till Monday, while the number of those affected crossed the 6,000 mark. Rajasthan has recorded 85 deaths and 2,263 cases while Gujarat reported 43 deaths and 898 people being infected with H1N1 virus. According to government data, Punjab reported 30 deaths and 250 cases of swine flu. The Union Ministry of Health on Wednesday recommended ...
Nearly 1,100 swine flu cases in Delhi; six deaths this year: Report
The death toll due to swine flu in Delhi has risen to six, even as 74 fresh cases of the HINI virus were recorded here on Wednesday, taking the total number of people affected by the disease in the city this year to 1,093, according to a report of the Directorate General of Health Services. The report also mentioned deaths of five more persons from co-morbidity, who had H1N1 infection. As per the report, of the six persons who have died of swine flu this year, one belonged to Delhi, while the rest five were residents of other cities, the report said. Amid the mounting cases of the H1N1 infections in the city, the Delhi government Wednesday issued a health advisory, prescribing the dos and don'ts. "Patients with co-morbid condition like low immunity, on immune-suppressant, blood cancer, renal transplant, diabetes, heart disease are at high risk of getting infected with swine flu," the advisory said. After the 74 fresh cases of H1N1 virus were recorded on Wednesday, the total number of .